3'(2'), 5'-Bisphosphate Nucleotidase 1 (BPNT1) (N-Term) Peptide
BPNT1
Reactivité: Humain
Hôte: Synthetic
BP, WB
N° du produit ABIN973866
150,78 €
Plus frais de livraison 40,00 € et TVA
100 μg
Destination:
France
Envoi sous 15 à 22 jours ouvrables
Aperçu rapide pour 3'(2'), 5'-Bisphosphate Nucleotidase 1 (BPNT1) (N-Term) Peptide (ABIN973866)
Antigène
BPNT1
(3'(2'), 5'-Bisphosphate Nucleotidase 1 (BPNT1))
Origine
Humain
Source
Synthetic
Application
Blocking Peptide (BP), Western Blotting (WB)
-
-
Protein Region
- N-Term
-
Attributs du produit
- This is a synthetic peptide designed for use in combination with anti-BPNT1 antibody (Catalog #: ARP58597_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
-
Purification
- Purified
-
-
-
-
Indications d'application
- Each Investigator should determine their own optimal working dilution for specific applications.
-
Restrictions
- For Research Use only
-
-
-
Format
- Lyophilized
-
Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
-
Concentration
- 1 mg/mL
-
Buffer
- Final peptide concentration is 1 mg/mL in PBS.
-
Conseil sur la manipulation
- Avoid repeated freeze-thaw cycles.
-
Stock
- -20 °C
-
Stockage commentaire
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
-
-
- BPNT1 (3'(2'), 5'-Bisphosphate Nucleotidase 1 (BPNT1))
-
Sujet
-
BPNT1, also called bisphosphate 3-prime-nucleotidase, or BPntase, is a member of a magnesium-dependent phosphomonoesterase family. Lithium, a major drug used to treat manic depression, acts as an uncompetitive inhibitor of BPntase. The predicted human protein is 92 % identical to mouse BPntase. BPntase's physiologic role in nucleotide metabolism may be regulated by inositol signaling pathways. The inhibition of human BPntase may account for lithium-induced nephrotoxicity.BPNT1, also called bisphosphate 3-prime-nucleotidase, or BPntase, is a member of a magnesium-dependent phosphomonoesterase family. Lithium, a major drug used to treat manic depression, acts as an uncompetitive inhibitor of BPntase. The predicted human protein is 92 % identical to mouse BPntase. BPntase's physiologic role in nucleotide metabolism may be regulated by inositol signaling pathways. The inhibition of human BPntase may account for lithium-induced nephrotoxicity.
Alias Symbols: PIP
Protein Size: 261 -
Poids moléculaire
- 29 kDa
-
ID gène
- 10380
-
NCBI Accession
- NM_006085, NP_006076
-
UniProt
- O95861
Antigène
-
Vous êtes ici:
