Bromodomain Containing 4 (BRD4) Peptide
BRD4
Reactivité: Humain
Hôte: Synthetic
BP, WB, ChIP, IF
N° du produit ABIN973879
Aperçu rapide pour Bromodomain Containing 4 (BRD4) Peptide (ABIN973879)
Antigène
BRD4
(Bromodomain Containing 4 (BRD4))
Origine
Humain
Source
Synthetic
Application
Blocking Peptide (BP), Western Blotting (WB), Chromatin Immunoprecipitation (ChIP), Immunofluorescence (IF)
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Attributs du produit
- This is a synthetic peptide designed for use in combination with anti-BRD4 antibody (Catalog #: ARP39076_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Purification
- Purified
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Indications d'application
- Each Investigator should determine their own optimal working dilution for specific applications.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Concentration
- 1 mg/mL
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Buffer
- Final peptide concentration is 1 mg/mL in PBS.
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Conseil sur la manipulation
- Avoid repeated freeze-thaw cycles.
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Stock
- -20 °C
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Stockage commentaire
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- BRD4 (Bromodomain Containing 4 (BRD4))
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Sujet
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BRD4 is homologous to the murine protein MCAP, which associates with chromosomes during mitosis, and to the human RING3 protein, a serine/threonine kinase. Each of these proteins contains two bromodomains, a conserved sequence motif which may be involved in chromatin targeting.The protein encoded by this gene is homologous to the murine protein MCAP, which associates with chromosomes during mitosis, and to the human RING3 protein, a serine/threonine kinase. Each of these proteins contains two bromodomains, a conserved sequence motif which may be involved in chromatin targeting. This gene has been implicated as the chromosome 19 target of translocation t(15,19)(q13,p13.1), which defines an upper respiratory tract carcinoma in young people. Two alternatively spliced transcript variants have been described.
Alias Symbols: CAP, HUNKI, MCAP, HUNK1
Protein Interaction Partner: E2,C7orf25,CHFR,CLDN1,PRPF40A,RFC1,RFC4,CCNT1,CCNT2,CDK9,HEXIM1,HIST2H3C,HIST2H4A,HIST4H4,MED12,MED14,MED17,MED24,RFC1,RFC2,RFC3,RFC4,RFC5,SIPA1
Protein Size: 722 -
Poids moléculaire
- 80 kDa
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ID gène
- 23476
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NCBI Accession
- NM_014299, NP_055114
Antigène
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