Caspase Recruitment Domain Family, Member 17 (CARD17) (Middle Region) Peptide
CARD17
Reactivité: Humain
Hôte: Synthetic
BP, WB
N° du produit ABIN974462
Aperçu rapide pour Caspase Recruitment Domain Family, Member 17 (CARD17) (Middle Region) Peptide (ABIN974462)
Antigène
CARD17
(Caspase Recruitment Domain Family, Member 17 (CARD17))
Origine
Humain
Source
Synthetic
Application
Blocking Peptide (BP), Western Blotting (WB)
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Protein Region
- Middle Region
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Séquence
- MDKARALLDS VIRKGAPACQ ICITYICEED SHLAGTLGLS AGPTSGNHLT
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Attributs du produit
- This is a synthetic peptide designed for use in combination with anti-CARD17 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Purification
- Purified
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Indications d'application
- Each Investigator should determine their own optimal working dilution for specific applications.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Concentration
- 1 mg/mL
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Buffer
- Final peptide concentration is 1 mg/mL in PBS.
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Conseil sur la manipulation
- Avoid repeated freeze-thaw cycles.
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Stock
- -20 °C
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Stockage commentaire
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- CARD17 (Caspase Recruitment Domain Family, Member 17 (CARD17))
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Sujet
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As a regulator of procaspase-1/CASP1 activation, CARD17 is implicated in the regulation of the proteolytic maturation of pro-IL-1beta/IL1B and its release during inflammation. CARD17 inhibits the release of IL1B in response to LPS in monocytes. However, unlike CASP1, CARD17 do not induce NF-kappa-B activation.
Alias Symbols: INCA
Protein Interaction Partner: CARD16,CARD17,CARD18,CASP1
Protein Size: 110 -
Poids moléculaire
- 12 kDa
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ID gène
- 440068
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NCBI Accession
- NM_001007232, NP_001007233
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UniProt
- Q5XLA6
Antigène
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