Caspase 7, Apoptosis-Related Cysteine Peptidase (CASP7) (N-Term) Peptide
CASP7
Reactivité: Humain
Hôte: Synthetic
BP, WB
N° du produit ABIN974478
Aperçu rapide pour Caspase 7, Apoptosis-Related Cysteine Peptidase (CASP7) (N-Term) Peptide (ABIN974478)
Antigène
Caspase 7 (CASP7)
(Caspase 7, Apoptosis-Related Cysteine Peptidase (CASP7))
Origine
Humain
Source
Synthetic
Application
Blocking Peptide (BP), Western Blotting (WB)
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Protein Region
- N-Term
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Séquence
- NNKNFDKVTG MGVRNGTDKD AEALFKCFRS LGFDVIVYND CSCAKMQDLL
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Attributs du produit
- This is a synthetic peptide designed for use in combination with anti-CASP7 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Purification
- Purified
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Indications d'application
- Each Investigator should determine their own optimal working dilution for specific applications.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Concentration
- 1 mg/mL
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Buffer
- Final peptide concentration is 1 mg/mL in PBS.
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Conseil sur la manipulation
- Avoid repeated freeze-thaw cycles.
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Stock
- -20 °C
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Stockage commentaire
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Caspase 7 (CASP7) (Caspase 7, Apoptosis-Related Cysteine Peptidase (CASP7))
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Sujet
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This gene encodes a protein which is a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce two subunits, large and small, that dimerize to form the active enzyme. The precursor of this caspase is cleaved by caspase 3 and 10. It is activated upon cell death stimuli and induces apoptosis. Alternative splicing results in four transcript variants, encoding three distinct isoforms.
Alias Symbols: CMH-1, ICE-LAP3, MCH3
Protein Interaction Partner: AR,ATN1,BIRC3,CTSG,GZMB,HTT,PARP1,PSEN1,RB1,XIAP,AR,BIRC2,BIRC3,BIRC5,BIRC7,CASP10,CASP2,CASP7,CAST,CDC42,CFLAR,CLSPN,CTSG,DCTN1,DFFA,DSP,EIF2AK2,GOLGA3,GORASP1,GZMB,HSPA5,KRT18,LYN,MAPT,MAX,MEF2A,MEF2D,NEDD4,PRKCZ,PSEN1,PSEN2,PSIP1,PSME3,PTMA,RAC1,RAD21,
Protein Size: 336 -
Poids moléculaire
- 37 kDa
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ID gène
- 840
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NCBI Accession
- NM_033338, NP_203124
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UniProt
- P55210
Antigène
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