CD274 (PD-L1) (C-Term) Peptide
PD-L1
Reactivité: Humain
Hôte: Synthetic
BP, WB
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- Antigène Tous les produits PD-L1
- PD-L1 (CD274 (PD-L1))
- Protein Region
- C-Term
- Origine
- Humain
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB)
- Séquence
- NVTSTLRINT TTNEIFYCTF RRLDPEENHT AELVIPELPL AHPPNERTHL
- Attributs du produit
- This is a synthetic peptide designed for use in combination with anti-CD274 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- Purification
- Purified
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- Indications d'application
- Each Investigator should determine their own optimal working dilution for specific applications.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Concentration
- 1 mg/mL
- Buffer
- Final peptide concentration is 1 mg/mL in PBS.
- Conseil sur la manipulation
- Avoid repeated freeze-thaw cycles.
- Stock
- -20 °C
- Stockage commentaire
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Antigène
- PD-L1 (CD274 (PD-L1))
- Synonymes
- B7-H Peptide, B7H1 Peptide, PD-L1 Peptide, PDCD1L1 Peptide, PDCD1LG1 Peptide, PDL1 Peptide, A530045L16Rik Peptide, B7h1 Peptide, Pdcd1l1 Peptide, Pdcd1lg1 Peptide, Pdl1 Peptide, RGD1566211 Peptide, CD274 molecule Peptide, CD274 antigen Peptide, programmed cell death 1 ligand 2 Peptide, CD274 Peptide, Cd274 Peptide, PDCD1LG2 Peptide
- Sujet
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CD274 is involved in the costimulatory signal, essential for T-cell proliferation and production of IL10 and IFNG, in an IL2-dependent and a PDCD1-independent manner. Interaction with PDCD1 inhibits T-cell proliferation and cytokine production.
Alias Symbols: B7-H, B7H1, MGC142294, MGC142296, PD-L1, PDCD1L1, PDCD1LG1, PDL1
Protein Interaction Partner: PDCD1,PDCD1
Protein Size: 290 - Poids moléculaire
- 32 kDa
- ID gène
- 29126
- NCBI Accession
- NM_014143, NP_054862
- UniProt
- Q9NZQ7
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