CD3 epsilon (CD3E) (Middle Region) Peptide
CD3E
Reactivité: Humain
Hôte: Synthetic
BP, WB
N° du produit ABIN974673
Aperçu rapide pour CD3 epsilon (CD3E) (Middle Region) Peptide (ABIN974673)
Antigène
CD3 epsilon (CD3E)
Origine
Humain
Source
Synthetic
Application
Blocking Peptide (BP), Western Blotting (WB)
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Protein Region
- Middle Region
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Séquence
- QYPGSEILWQ HNDKNIGGDE DDKNIGSDED HLSLKEFSEL EQSGYYVCYP
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Attributs du produit
- This is a synthetic peptide designed for use in combination with anti-CD3E Antibody(ARP59097_P050),. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Purification
- Purified
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Indications d'application
- Each Investigator should determine their own optimal working dilution for specific applications.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Concentration
- 1 mg/mL
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Buffer
- Final peptide concentration is 1 mg/mL in PBS.
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Conseil sur la manipulation
- Avoid repeated freeze-thaw cycles.
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Stock
- -20 °C
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Stockage commentaire
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- CD3 epsilon (CD3E)
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Sujet
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The protein encoded by this gene is the CD3-epsilon polypeptide, which together with CD3-gamma, -delta and -zeta, and the T-cell receptor alpha/beta and gamma/delta heterodimers, forms the T-cell receptor-CD3 complex. This complex plays an important role in coupling antigen recognition to several intracellular signal-transduction pathways. The genes encoding the epsilon, gamma and delta polypeptides are located in the same cluster on chromosome 11. The epsilon polypeptide plays an essential role in T-cell development. Defects in this gene cause immunodeficiency. This gene has also been linked to a susceptibility to type I diabetes in women.
Alias Symbols: FLJ18683, T3E, TCRE
Protein Interaction Partner: CD3D,CD3EAP,CD3G,CD79B,LCK,NCK1,NCK2,NCL,PIK3R1,PTPN22,SHC1,SYK,TOP2B,TRAT1,UNC119,ZAP70,CD3EAP,CD3G,JAK3,NCK1,NCK2,NCL,PIK3R1,SYK,TOP2B,ZAP70
Protein Size: 207 -
Poids moléculaire
- 23 kDa
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ID gène
- 916
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NCBI Accession
- NM_000733, NP_000724
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UniProt
- P07766
Antigène
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