This is a synthetic peptide designed for use in combination with anti-CDC23 antibody (Catalog #: ARP43039_T100). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
CDC23 shares strong similarity with Saccharomyces cerevisiae Cdc23, a protein essential for cell cycle progression through the G2/M transition. This protein is a component of anaphase-promoting complex (APC), which is composed of eight protein subunits and highly conserved in eukaryotic cells. APC catalyzes the formation of cyclin B-ubiquitin conjugate that is responsible for the ubiquitin-mediated proteolysis of B-type cyclins. This protein and 3 other members of the APC complex contain the TPR (tetratricopeptide repeat), a protein domain important for protein-protein interaction.
Alias Symbols: APC8, CUT23, ANAPC8
Protein Interaction Partner: ANAPC10,CDC16,RAD54B,RBPMS,TSC22D4,ANAPC1,ANAPC4,APC2,CDC20,CDC27,CDH1,CDT1,RAD54B,RBPMS,TSC22D4