Cartilage Intermediate Layer Protein, Nucleotide Pyrophosphohydrolase (CILP) (C-Term) Peptide
CILP
Reactivité: Humain
Hôte: Synthetic
BP, WB
N° du produit ABIN974989
150,78 €
Plus frais de livraison 40,00 € et TVA
100 μg
Destination:
France
Envoi sous 15 à 22 jours ouvrables
Aperçu rapide pour Cartilage Intermediate Layer Protein, Nucleotide Pyrophosphohydrolase (CILP) (C-Term) Peptide (ABIN974989)
Antigène
CILP
(Cartilage Intermediate Layer Protein, Nucleotide Pyrophosphohydrolase (CILP))
Origine
Humain
Source
Synthetic
Application
Blocking Peptide (BP), Western Blotting (WB)
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Protein Region
- C-Term
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Séquence
- YIKVKIVGPL EVNVRSRNMG GTHRQTVGKL YGIRDVRSTR DRDQPNVSAA
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Attributs du produit
- This is a synthetic peptide designed for use in combination with anti-CILP Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Purification
- Purified
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Cartilage Intermediate Layer Protein, Nucleotide Pyrophosphohydrolase (CILP) peptide
CILP Reactivité: Humain, Rat, Chien, Souris Hôte: Synthetic BP, Imm
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Indications d'application
- Each Investigator should determine their own optimal working dilution for specific applications.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Concentration
- 1 mg/mL
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Buffer
- Final peptide concentration is 1 mg/mL in PBS.
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Conseil sur la manipulation
- Avoid repeated freeze-thaw cycles.
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Stock
- -20 °C
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Stockage commentaire
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- CILP (Cartilage Intermediate Layer Protein, Nucleotide Pyrophosphohydrolase (CILP))
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Sujet
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Major alterations in the composition of the cartilage extracellular matrix occur in joint disease, such as osteoarthrosis. This gene encodes the cartilage intermediate layer protein (CILP), which increases in early osteoarthrosis cartilage. The encoded protein was thought to encode a protein precursor for two different proteins, an N-terminal CILP and a C-terminal homolog of NTPPHase, however, later studies identified no nucleotide pyrophosphatase phosphodiesterase (NPP) activity. The full-length and the N-terminal domain of this protein was shown to function as an IGF-1 antagonist. An allelic variant of this gene has been associated with lumbar disc disease.
Alias Symbols: CILP-1, HsT18872
Protein Size: 1184 -
Poids moléculaire
- 52 kDa
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ID gène
- 8483
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NCBI Accession
- NM_003613, NP_003604
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UniProt
- O75339
Antigène
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