Coatomer Protein Complex, Subunit alpha (COPA) Peptide
COPA
Reactivité: Humain
Hôte: Synthetic
BP, WB
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- Antigène Tous les produits COPA
- COPA (Coatomer Protein Complex, Subunit alpha (COPA))
- Origine
- Humain
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB)
- Attributs du produit
- This is a synthetic peptide designed for use in combination with anti-COPA antibody (Catalog #: ARP51893_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- Purification
- Purified
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- Indications d'application
- Each Investigator should determine their own optimal working dilution for specific applications.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Concentration
- 1 mg/mL
- Buffer
- Final peptide concentration is 1 mg/mL in PBS.
- Conseil sur la manipulation
- Avoid repeated freeze-thaw cycles.
- Stock
- -20 °C
- Stockage commentaire
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Antigène
- COPA (Coatomer Protein Complex, Subunit alpha (COPA))
- Synonymes
- COPA Peptide, DDBDRAFT_0189693 Peptide, DDBDRAFT_0233797 Peptide, DDB_0189693 Peptide, DDB_0233797 Peptide, DKFZp469O221 Peptide, AU040324 Peptide, xenin Peptide, HEP-COP Peptide, cb281 Peptide, fb13c12 Peptide, wu:fb13c12 Peptide, coatomer protein complex subunit alpha Peptide, WD40 repeat-containing protein Peptide, Coatomer subunit alpha Peptide, coatomer protein complex, subunit alpha Peptide, coatomer protein complex subunit alpha L homeolog Peptide, COPA Peptide, copA Peptide, cgd8_860 Peptide, Chro.80105 Peptide, AFUA_3G08840 Peptide, copa Peptide, Copa Peptide, copa.L Peptide
- Sujet
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In eukaryotic cells, protein transport between the endoplasmic reticulum and Golgi compartments is mediated in part by non-clathrin-coated vesicular coat proteins (COPs). Seven coat proteins have been identified, and they represent subunits of a complex known as coatomer. The subunits are designated alpha-COP, beta-COP, beta-prime-COP, gamma-COP, delta-COP, epsilon-COP, and zeta-COP. The alpha-COP, encoded by COPA, shares high sequence similarity with RET1P, the alpha subunit of the coatomer complex in yeast. Also, the N-terminal 25 amino acids of alpha-COP encode the bioactive peptide, xenin, which stimulates exocrine pancreatic secretion and may act as a gastrointestinal hormone.In eukaryotic cells, protein transport between the endoplasmic reticulum and Golgi compartments is mediated in part by non-clathrin-coated vesicular coat proteins (COPs). Seven coat proteins have been identified, and they represent subunits of a complex known as coatomer. The subunits are designated alpha-COP, beta-COP, beta-prime-COP, gamma-COP, delta-COP, epsilon-COP, and zeta-COP. The alpha-COP, encoded by COPA, shares high sequence similarity with RET1P, the alpha subunit of the coatomer complex in yeast. Also, the N-terminal 25 amino acids of alpha-COP encode the bioactive peptide, xenin, which stimulates exocrine pancreatic secretion and may act as a gastrointestinal hormone. Alternative splicing results in multiple splice forms encoding distinct isoforms.
Alias Symbols: FLJ26320, HEP-COP
Protein Interaction Partner: COPE,SACM1L,ARCN1,ARFGAP1,COPB2,COPE,MTNR1B,PDGFRB,SACM1L,SLC25A11,STX8,TMED2,ARFGAP1,BET1L,COPB1,COPB2,COPE,PDGFRB,SLC25A11,USP49
Protein Size: 1224 - Poids moléculaire
- 135 kDa
- ID gène
- 1314
- NCBI Accession
- NM_004371, NP_004362
- UniProt
- P53621
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