COPB1
(Coatomer Protein Complex, Subunit beta 1 (COPB1))
Origine
Humain
Source
Synthetic
Application
Blocking Peptide (BP), Western Blotting (WB)
Attributs du produit
This is a synthetic peptide designed for use in combination with anti-COPB1 antibody (Catalog #: ARP52371_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin-coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins. In mammals, the coatomer can only be recruited by membranes associated to ADP-ribosylation factors (ARFs), which are small GTP-binding proteins, the complex also influences the Golgi structural integrity, as well as the processing, activity, and endocytic recycling of LDL receptors.
Alias Symbols: COPB, DKFZp761K102, FLJ10341
Protein Interaction Partner: ADAM19,ARCN1,nef,ADAM19,ARCN1,ARF1,COPE,COPG,COPG2,HLA-G,KCNK3,KDELR1,PDGFRB,PRKCE,RGS2,RGS4,RHOQ,TAPBP,TRIM37,UBQLN4,ADAM19,ARCN1,ARF1,COPA,COPB2,COPE,COPG,COPG2,HLA-A,HLA-G,KCNK3,KDELR1,PMS2,TAP1,TAPBP,TRIM37