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CAMP Responsive Element Modulator (CREM) Peptide

CREM Reactivité: Humain Hôte: Synthetic BP, WB
N° du produit ABIN975303
  • Antigène Tous les produits CREM
    CREM (CAMP Responsive Element Modulator (CREM))
    Origine
    Humain
    Source
    • 6
    Synthetic
    Application
    Blocking Peptide (BP), Western Blotting (WB)
    Attributs du produit
    This is a synthetic peptide designed for use in combination with anti-CREM antibody (Catalog #: ARP34777_T100). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
    Purification
    Purified
  • Indications d'application
    Each Investigator should determine their own optimal working dilution for specific applications.
    Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
    Concentration
    1 mg/mL
    Buffer
    Final peptide concentration is 1 mg/mL in PBS.
    Conseil sur la manipulation
    Avoid repeated freeze-thaw cycles.
    Stock
    -20 °C
    Stockage commentaire
    For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
  • Antigène
    CREM (CAMP Responsive Element Modulator (CREM))
    Synonymes
    CREM Peptide, ICER Peptide, CREM-2 Peptide, hCREM-2 Peptide, ICERI Peptide, Icer Peptide, cAMP responsive element modulator Peptide, CREM Peptide, Crem Peptide
    Sujet
    CREM is a bZIP transcription factor that binds to the cAMP responsive element found in many viral and cellular promoters. It is an important component of cAMP-mediated signal transduction during the spermatogenetic cycle, as well as other complex processes. Alternative promoter and translation initiation site usage allows this gene to exert spatial and temporal specificity to cAMP responsiveness. Multiple alternatively spliced transcript variants encoding several different isoforms have been found for this gene, with some of them functioning as activators and some as repressors of transcription.

    Alias Symbols: ICER, CREM-2, hCREM-2

    Protein Interaction Partner: CDC34,CREB1,FHL5,KCNIP3,SPI1,TAF4,TBP,ATF1,CAMK2D,CAMK2G,CDC34,CDK1,CREB1,CREB3L1,CREBBP,CREM,CSNK1A1,CSNK2A1,CSNK2A2,FHL5,GSK3A,GSK3B,KCNIP3,PRKACA,PRKCA,SPI1,TAF4,TBP,CD34,FHL5,KCNIP3,SPI1,TAF4,TBP

    Protein Size: 120
    Poids moléculaire
    13 kDa
    ID gène
    1390
    NCBI Accession
    NM_182717, NP_874386
    UniProt
    O75519
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