×
Pour une meilleure utilisation, nous vous conseillons d’activer Javascript dans votre navigateur.
V-Crk Sarcoma Virus CT10 Oncogene Homolog (Avian)-Like (CRKL) (Middle Region) Peptide
CRKL
Reactivité: Humain
Hôte: Synthetic
BP, WB
Détail du produit
(cache)
Antigène
Tous les produits CrkL (CRKL)
CrkL (CRKL)
(V-Crk Sarcoma Virus CT10 Oncogene Homolog (Avian)-Like (CRKL))
Protein Region
Middle Region
Origine
Humain
Source
Toutes les hôtes sur CrkL Peptides
Synthetic
Application
Blocking Peptide (BP), Western Blotting (WB)
Séquence
RSSPHGKHGN RNSNSYGIPE PAHAYAQPQT TTPLPAVSGS PGAAITPLPS
Attributs du produit
This is a synthetic peptide designed for use in combination with anti-CRKL Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
Purification
Purified
Alternatives
(show)
Information d'application
(cache)
Indications d'application
Each Investigator should determine their own optimal working dilution for specific applications.
Restrictions
For Research Use only
Stockage
(cache)
Format
Lyophilized
Reconstitution
Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
Concentration
1 mg/mL
Buffer
Final peptide concentration is 1 mg/mL in PBS.
Conseil sur la manipulation
Avoid repeated freeze-thaw cycles.
Stock
-20 °C
Stockage commentaire
For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
Détail du antigène
(cache)
Antigène
CrkL (CRKL)
(V-Crk Sarcoma Virus CT10 Oncogene Homolog (Avian)-Like (CRKL))
Synonymes
CRKL Peptide, wu:fa55g05 Peptide, wu:fj60e01 Peptide, zgc:63469 Peptide, 1110025F07Rik Peptide, AA589403 Peptide, AI325100 Peptide, Crkol Peptide, CRK like proto-oncogene, adaptor protein Peptide, v-crk avian sarcoma virus CT10 oncogene homolog-like Peptide, CRKL Peptide, crkl Peptide, Crkl Peptide
Sujet
CRKL has been shown to activate the RAS and JUN kinase signaling pathways and transform fibroblasts in a RAS-dependent fashion. It is a substrate of the BCR-ABL tyrosine kinase and plays a role in fibroblast transformation by BCR-ABL. In addition, CRKL has oncogenic potential. Alias Symbols: - Protein Size: 303
Poids moléculaire
34 kDa
ID gène
1399
NCBI Accession
NM_005207 , NP_005198
UniProt
P46109
Vus récemment
(cache)