Crystallin, alpha B (CRYAB) Peptide
CRYAB
Reactivité: Humain
Hôte: Synthetic
BP, WB
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- Antigène Tous les produits CRYAB
- CRYAB (Crystallin, alpha B (CRYAB))
- Origine
- Humain
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB)
- Attributs du produit
- This is a synthetic peptide designed for use in combination with anti-CRYAB antibody (Catalog #: ARP48196_T100). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- Purification
- Purified
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Crystallin, alpha B (CRYAB) peptide
CRYAB Reactivité: Humain, Souris, Rat Hôte: Synthetic BP, Imm
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- Indications d'application
- Each Investigator should determine their own optimal working dilution for specific applications.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Concentration
- 1 mg/mL
- Buffer
- Final peptide concentration is 1 mg/mL in PBS.
- Conseil sur la manipulation
- Avoid repeated freeze-thaw cycles.
- Stock
- -20 °C
- Stockage commentaire
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Antigène
- CRYAB (Crystallin, alpha B (CRYAB))
- Synonymes
- CMD1II Peptide, CRYA2 Peptide, CTPP2 Peptide, CTRCT16 Peptide, HSPB5 Peptide, MFM2 Peptide, Crya-2 Peptide, Crya2 Peptide, HspB5 Peptide, AACRYA Peptide, CRYAB Peptide, cryab Peptide, cryab2 Peptide, wu:fe37f08 Peptide, zgc:91937 Peptide, crystallin alpha B Peptide, crystallin, alpha B Peptide, hypothetical protein Peptide, crystallin, alpha B, a Peptide, crystallin, alpha B, b Peptide, CRYAB Peptide, Cryab Peptide, ZK1128.7 Peptide, cryaba Peptide, cryabb Peptide
- Sujet
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Alpha crystallins are composed of: alpha-A and alpha-B, for acidic and basic, respectively. They act as molecular chaperones although they do not renature proteins and release them in the fashion of a true chaperone, instead they hold them in large soluble aggregates. Post-translational modifications decrease the ability to chaperone. Two additional functions of alpha crystallins are an autokinase activity and participation in the intracellular architecture. Alpha-A and alpha-B are differentially expressed, alpha-A is preferentially restricted to the lens and alpha-B is expressed widely in many tissues and organs. Elevated expression of alpha-B crystallin occurs in many neurological diseases, a missense mutation cosegregated in a family with a desmin-related myopathy.
Alias Symbols: CRYA2, CTPP2, HSPB5
Protein Interaction Partner: BAX,BCL2L1,APP,BCL2L1,BMPR2,CRYAA,CRYAB,CRYBB2,CRYGC,CS,EPB41,HSPB1,PSMA3,TTN,BMPR2,CRYAA,CRYAB,CRYBB2,CRYGC,CS,HSPB1,HSPB2,PSMA3
Protein Size: 108 - Poids moléculaire
- 12 kDa
- ID gène
- 1410
- NCBI Accession
- NM_001885
- UniProt
- P02511
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