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Kv Channel Interacting Protein 3, Calsenilin (KCNIP3) Peptide

KCNIP3 Reactivité: Humain Hôte: Synthetic BP, WB, IHC
N° du produit ABIN975353
  • Antigène Tous les produits DREAM (KCNIP3)
    DREAM (KCNIP3) (Kv Channel Interacting Protein 3, Calsenilin (KCNIP3))
    Origine
    Humain
    Source
    • 7
    Synthetic
    Application
    Blocking Peptide (BP), Western Blotting (WB), Immunohistochemistry (IHC)
    Attributs du produit
    This is a synthetic peptide designed for use in combination with anti-CSEN antibody (Catalog #: ARP31932_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
    Purification
    Purified
  • Indications d'application
    Each Investigator should determine their own optimal working dilution for specific applications.
    Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
    Concentration
    1 mg/mL
    Buffer
    Final peptide concentration is 1 mg/mL in PBS.
    Conseil sur la manipulation
    Avoid repeated freeze-thaw cycles.
    Stock
    -20 °C
    Stockage commentaire
    For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
  • Antigène
    DREAM (KCNIP3) (Kv Channel Interacting Protein 3, Calsenilin (KCNIP3))
    Synonymes
    CSEN Peptide, DREAM Peptide, KCHIP3 Peptide, 4933407H12Rik Peptide, AI413860 Peptide, Csen Peptide, KChIP3 Peptide, R74849 Peptide, Dream Peptide, rKChIP3 Peptide, csen Peptide, im:7145308 Peptide, kcnip3 Peptide, zgc:73306 Peptide, KCNIP3 Peptide, potassium voltage-gated channel interacting protein 3 Peptide, Kv channel-interacting protein 4 Peptide, calsenilin Peptide, Kv channel interacting protein 3, calsenilin Peptide, Kv channel interacting protein 3b, calsenilin Peptide, KCNIP3 Peptide, LOC5568664 Peptide, CpipJ_CPIJ002549 Peptide, Tsp_05009 Peptide, Kcnip3 Peptide, kcnip3b Peptide, kcnip3 Peptide
    Sujet
    CSEN is a member of the family of voltage-gated potassium (Kv) channel-interacting proteins (KCNIPs), which belong to the recoverin branch of the EF-hand superfamily. Members of the KCNIP family are small calcium binding proteins. They all have EF-hand-like domains, and differ from each other in the N-terminus. They are integral subunit components of native Kv4 channel complexes. They may regulate A-type currents, and hence neuronal excitability, in response to changes in intracellular calcium. The protein encoded by this gene is also shown to function as a calcium-regulated transcriptional repressor, and to interact with presenilins. Mutations in the presenilin genes have been implicated in Alzheimer's disease.

    Alias Symbols: CSEN, DREAM, KCHIP3

    Protein Interaction Partner: CASP3,CD177,CREB1,CREM,PSEN1,PSEN2,CD177,CREB1,CREM,CRK,PSEN1,PSEN2

    Protein Size: 256
    Poids moléculaire
    29 kDa
    ID gène
    30818
    NCBI Accession
    NM_013434, NP_038462
    UniProt
    Q9Y2W7
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