Cathepsin K (CTSK) (Middle Region) Peptide
CTSK
Reactivité: Humain
Hôte: Synthetic
BP, WB
N° du produit ABIN975444
Aperçu rapide pour Cathepsin K (CTSK) (Middle Region) Peptide (ABIN975444)
Antigène
Cathepsin K (CTSK)
Origine
Humain
Source
Synthetic
Application
Blocking Peptide (BP), Western Blotting (WB)
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Protein Region
- Middle Region
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Séquence
- SPQNLVDCVS ENDGCGGGYM TNAFQYVQKN RGIDSEDAYP YVGQEESCMY
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Attributs du produit
- This is a synthetic peptide designed for use in combination with anti-CTSK Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Purification
- Purified
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Cathepsin K (CTSK) peptide
CTSK Reactivité: Humain, Boeuf (Vache), Chien, Souris, Rat, Porc Hôte: Synthetic BP, Imm
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Indications d'application
- Each Investigator should determine their own optimal working dilution for specific applications.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Concentration
- 1 mg/mL
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Buffer
- Final peptide concentration is 1 mg/mL in PBS.
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Conseil sur la manipulation
- Avoid repeated freeze-thaw cycles.
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Stock
- -20 °C
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Stockage commentaire
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Cathepsin K (CTSK)
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Sujet
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The protein encoded by this gene is a lysosomal cysteine proteinase involved in bone remodeling and resorption. This protein, which is a member of the peptidase C1 protein family, is predominantly expressed in osteoclasts. However, the encoded protein is also expressed in a significant fraction of human breast cancers, where it could contribute to tumor invasiveness. Mutations in this gene are the cause of pycnodysostosis, an autosomal recessive disease characterized by osteosclerosis and short stature. This gene may be subject to RNA editing.
Alias Symbols: CTS02, CTSO, CTSO1, CTSO2, MGC23107, PKND, PYCD
Protein Interaction Partner: FGFR3,KNG1,SERPINB13,SERPINB3,SPARC,FGFR3,SERPINB3
Protein Size: 329 -
Poids moléculaire
- 37 kDa
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ID gène
- 1513
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NCBI Accession
- NM_000396, NP_000387
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UniProt
- P43235
Antigène
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