Chemokine (C-X-C Motif) Receptor 4 (CXCR4) Peptide
CXCR4
Reactivité: Humain
Hôte: Synthetic
BP, WB, IHC, FACS
N° du produit ABIN975479
150,78 €
Plus frais de livraison 40,00 € et TVA
100 μg
Destination:
France
Envoi sous 15 à 22 jours ouvrables
Aperçu rapide pour Chemokine (C-X-C Motif) Receptor 4 (CXCR4) Peptide (ABIN975479)
Antigène
CXCR4
(Chemokine (C-X-C Motif) Receptor 4 (CXCR4))
Origine
Humain
Source
Synthetic
Application
Blocking Peptide (BP), Western Blotting (WB), Immunohistochemistry (IHC), Flow Cytometry (FACS)
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Attributs du produit
- This is a synthetic peptide designed for use in combination with anti-CXCR4 antibody (Catalog #: ARP30799_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Purification
- Purified
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Chemokine (C-X-C Motif) Receptor 4 (CXCR4) peptide
CXCR4 Hôte: Synthetic BP, WB, IHC
Chemokine (C-X-C Motif) Receptor 4 (CXCR4) (AA 26-37) peptide (Ovalbumin)CXCR4 Reactivité: Humain Hôte: Synthetic WB, Imm, SDS
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Indications d'application
- Each Investigator should determine their own optimal working dilution for specific applications.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Concentration
- 1 mg/mL
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Buffer
- Final peptide concentration is 1 mg/mL in PBS.
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Conseil sur la manipulation
- Avoid repeated freeze-thaw cycles.
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Stock
- -20 °C
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Stockage commentaire
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- CXCR4 (Chemokine (C-X-C Motif) Receptor 4 (CXCR4))
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Sujet
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CXCR4 is a CXC chemokine receptor specific for stromal cell-derived factor-1. The protein has 7 transmembrane regions and is located on the cell surface. It acts with the CD4 protein to support HIV entry into cells and is also highly expressed in breast cancer cells. Mutations in this gene have been associated with WHIM (warts, hypogammaglobulinemia, infections, and myelokathexis) syndrome. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.This gene encodes a CXC chemokine receptor specific for stromal cell-derived factor-1. The protein has 7 transmembrane regions and is located on the cell surface. It acts with the CD4 protein to support HIV entry into cells and is also highly expressed in breast cancer cells. Mutations in this gene have been associated with WHIM (warts, hypogammaglobulinemia, infections, and myelokathexis) syndrome. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.
Alias Symbols: CD184, D2S201E, FB22, HM89, HSY3RR, LAP3, LCR1, LESTR, NPY3R, NPYR, NPYRL, NPYY3R, WHIM
Protein Interaction Partner: CXCL12,ADRBK2,ARRB2,CCR5,CD4,CTSG,CXCL12,CXCR4,DPP4,ELANE,GNA13,GNAI1,HSPA8,JAK1,JAK2,JAK3,MYH9,PTK2,PTPN11,PTPN6,PTPRC,SDC4,SOCS1,SOCS3,STAT1,STAT2,STAT3,STAT5B,VAV1,ADRBK2,CCR5,CD4,ITCH,JAK2,JAK3,PTK2,PTPN6,SOCS3,UBC,USP14
Protein Size: 352 -
Poids moléculaire
- 40 kDa
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ID gène
- 7852
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NCBI Accession
- NM_003467, NP_003458
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UniProt
- P61073
Antigène
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