Dishevelled Associated Activator of Morphogenesis 1 (DAAM1) (Middle Region) Peptide
DAAM1
Reactivité: Humain
Hôte: Synthetic
BP, WB
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- Antigène Tous les produits DAAM1
- DAAM1 (Dishevelled Associated Activator of Morphogenesis 1 (DAAM1))
- Protein Region
- Middle Region
- Origine
- Humain
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB)
- Attributs du produit
- This is a synthetic peptide designed for use in combination with anti-DAAM1 antibody (Catalog #: ARP55131_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- Purification
- Purified
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- Indications d'application
- Each Investigator should determine their own optimal working dilution for specific applications.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Concentration
- 1 mg/mL
- Buffer
- Final peptide concentration is 1 mg/mL in PBS.
- Conseil sur la manipulation
- Avoid repeated freeze-thaw cycles.
- Stock
- -20 °C
- Stockage commentaire
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Antigène
- DAAM1 (Dishevelled Associated Activator of Morphogenesis 1 (DAAM1))
- Synonymes
- 1700066F09Rik Peptide, 2310028E21Rik Peptide, AI503486 Peptide, E130308H01 Peptide, mKIAA0666 Peptide, daam-1 Peptide, xdaam1 Peptide, daam1 Peptide, DAAM1 Peptide, DKFZp468D0524 Peptide, daam1l Peptide, fc83b10 Peptide, si:ch211-87i20.1 Peptide, wu:fc83b10 Peptide, dishevelled associated activator of morphogenesis 1 Peptide, dishevelled associated activator of morphogenesis 1 S homeolog Peptide, dishevelled associated activator of morphogenesis 1a Peptide, dishevelled associated activator of morphogenesis 1b Peptide, DAAM1 Peptide, Daam1 Peptide, daam1.S Peptide, daam1a Peptide, daam1 Peptide, daam1b Peptide
- Sujet
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Functions of the cell cortex, including motility, adhesion, and cytokinesis, are mediated by the reorganization of the actin cytoskeleton and recent evidence suggests a role for the Formin homology (FH) proteins in these processes. The protein encoded by this gene contains FH domains and belongs to a novel FH protein subfamily implicated in cell polarity. Wnt/Fz signaling activates the small GTPase Rho, a key regulator of cytoskeleton architecture, to control cell polarity and movement during development. Activation requires Dvl-Rho complex formation, an assembly mediated by this gene product, which is thought to function as a scaffolding protein.Functions of the cell cortex, including motility, adhesion, and cytokinesis, are mediated by the reorganization of the actin cytoskeleton and recent evidence suggests a role for the Formin homology (FH) proteins in these processes. The protein encoded by this gene contains FH domains and belongs to a novel FH protein subfamily implicated in cell polarity. Wnt/Fz signaling activates the small GTPase Rho, a key regulator of cytoskeleton architecture, to control cell polarity and movement during development. Activation requires Dvl-Rho complex formation, an assembly mediated by this gene product, which is thought to function as a scaffolding protein. Evidence of alternative splicing has been observed for this gene but the full-length nature of these variants has not been determined.
Alias Symbols: FLJ41657, KIAA0666
Protein Interaction Partner: DVL1,DVL2,RHOA
Protein Size: 1078 - Poids moléculaire
- 123 kDa
- ID gène
- 23002
- NCBI Accession
- NM_014992, NP_055807
- UniProt
- Q9Y4D1
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