DCP2 Decapping Enzyme Homolog (DCP2) Peptide
DCP2
Reactivité: Humain
Hôte: Synthetic
BP, WB
N° du produit ABIN975632
Aperçu rapide pour DCP2 Decapping Enzyme Homolog (DCP2) Peptide (ABIN975632)
Antigène
DCP2
(DCP2 Decapping Enzyme Homolog (DCP2))
Origine
Humain
Source
Synthetic
Application
Blocking Peptide (BP), Western Blotting (WB)
-
-
Attributs du produit
- This is a synthetic peptide designed for use in combination with anti-DCP2 antibody (Catalog #: ARP41150_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
-
Purification
- Purified
-
-
-
-
Indications d'application
- Each Investigator should determine their own optimal working dilution for specific applications.
-
Restrictions
- For Research Use only
-
-
-
Format
- Lyophilized
-
Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
-
Concentration
- 1 mg/mL
-
Buffer
- Final peptide concentration is 1 mg/mL in PBS.
-
Conseil sur la manipulation
- Avoid repeated freeze-thaw cycles.
-
Stock
- -20 °C
-
Stockage commentaire
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
-
-
- DCP2 (DCP2 Decapping Enzyme Homolog (DCP2))
-
Sujet
-
DCP2 is necessary for the degradation of mRNAs, both in normal mRNA turnover and in nonsense-mediated mRNA decay. DCP2 removes the 7-methyl guanine cap structure from mRNA molecules, yielding a 5'-phosphorylated mRNA fragment and 7m-GDP. It has higher activity towards mRNAs that lack a poly(A) tail, but has no activity towards a cap structure lacking a RNA moiety.DCP2 is a key component of an mRNA-decapping complex required for removal of the 5-prime cap from mRNA prior to its degradation from the 5-prime end (Fenger-Gron et al., 2005 [PubMed 16364915]).[supplied by OMIM]. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications. PRIMARYREFSEQ_SPAN PRIMARY_IDENTIFIER PRIMARY_SPAN COMP 1-539 AY135173.1 1-539 540-1992 AK090564.1 481-1933 1993-8947 AC008536.7 154323-161277
Alias Symbols: FLJ33245, NUDT20
Protein Interaction Partner: EIF2C1,EIF2C2,DCP1A,DCP1B,DCP2,EIF2C1,EIF2C2,NAGK,POLA2,PSMB1,UPF1,UPF2,DCP1A,PSMB1,UPF1,UPF2,UPF3A
Protein Size: 420 -
Poids moléculaire
- 48 kDa
-
ID gène
- 167227
-
NCBI Accession
- NM_152624, NP_689837
-
UniProt
- Q8IU60
Antigène
-
Vous êtes ici:
