Deformed Epidermal Autoregulatory Factor 1 (Drosophila) (DEAF1) Peptide
DEAF1
Reactivité: Humain
Hôte: Synthetic
BP, WB
N° du produit ABIN975714
Aperçu rapide pour Deformed Epidermal Autoregulatory Factor 1 (Drosophila) (DEAF1) Peptide (ABIN975714)
Antigène
DEAF1
(Deformed Epidermal Autoregulatory Factor 1 (Drosophila) (DEAF1))
Origine
Humain
Source
Synthetic
Application
Blocking Peptide (BP), Western Blotting (WB)
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Attributs du produit
- This is a synthetic peptide designed for use in combination with anti-DEAF1 antibody (Catalog #: ARP39468_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Purification
- Purified
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Indications d'application
- Each Investigator should determine their own optimal working dilution for specific applications.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Concentration
- 1 mg/mL
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Buffer
- Final peptide concentration is 1 mg/mL in PBS.
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Conseil sur la manipulation
- Avoid repeated freeze-thaw cycles.
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Stock
- -20 °C
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Stockage commentaire
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- DEAF1 (Deformed Epidermal Autoregulatory Factor 1 (Drosophila) (DEAF1))
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Sujet
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DEAF1 down-regulates transcription of those genes by binding to sequence with multiple copies of TTC[CG]G present in their own promoter and that of the HNRPA2B1 gene. DEAF1 binds to the retinoic acid response element (RARE) AGGGTTCACCGAAAGTTCA. DEAF1 activates the proenkephalin gene independently of promoter binding, probably through protein-protein interaction. When secreted, behaves as an inhibitor of cell proliferation, by arresting cells in the G0 or G1 phase.
Alias Symbols: SPN, NUDR, ZMYND5
Protein Interaction Partner: DEAF1,ASCC2,INTS1,ASCC2,LMO4
Protein Size: 565 -
Poids moléculaire
- 59 kDa
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ID gène
- 10522
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NCBI Accession
- NM_021008, NP_066288
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UniProt
- O75398
Antigène
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