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ATP-Dependent RNA Helicase A (DHX9) Peptide

DHX9 Reactivité: Humain Hôte: Synthetic BP, IHC, WB
N° du produit ABIN975790

Aperçu rapide pour ATP-Dependent RNA Helicase A (DHX9) Peptide (ABIN975790)

Antigène

DHX9 (ATP-Dependent RNA Helicase A (DHX9))

Origine

Humain

Source

  • 3
Synthetic

Application

Blocking Peptide (BP), Immunohistochemistry (IHC), Western Blotting (WB)
  • Attributs du produit

    This is a synthetic peptide designed for use in combination with anti-DHX9 antibody (Catalog #: ARP36343_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.

    Purification

    Purified
  • Indications d'application

    Each Investigator should determine their own optimal working dilution for specific applications.

    Restrictions

    For Research Use only
  • Format

    Lyophilized

    Reconstitution

    Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.

    Concentration

    1 mg/mL

    Buffer

    Final peptide concentration is 1 mg/mL in PBS.

    Conseil sur la manipulation

    Avoid repeated freeze-thaw cycles.

    Stock

    -20 °C

    Stockage commentaire

    For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
  • Antigène

    DHX9 (ATP-Dependent RNA Helicase A (DHX9))

    Sujet

    DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases. They are implicated in a number of cellular processes involving alteration of RNA secondary structure such as translation initiation, nuclear and mitochondrial splicing, and ribosome and spliceosome assembly. Based on their distribution patterns, some members of this family are believed to be involved in embryogenesis, spermatogenesis, and cellular growth and division. DHX9 is a DEAD box protein with RNA helicase activity. It may participate in melting of DNA:RNA hybrids, such as those that occur during transcription, and may play a role in X-linked gene expression.DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases. They are implicated in a number of cellular processes involving alteration of RNA secondary structure such as translation initiation, nuclear and mitochondrial splicing, and ribosome and spliceosome assembly. Based on their distribution patterns, some members of this family are believed to be involved in embryogenesis, spermatogenesis, and cellular growth and division. This gene encodes a DEAD box protein with RNA helicase activity. It may participate in melting of DNA:RNA hybrids, such as those that occur during transcription, and may play a role in X-linked gene expression. It contains 2 copies of a double-stranded RNA-binding domain, a DEXH core domain and an RGG box. The RNA-binding domains and RGG box influence and regulate RNA helicase activity.

    Alias Symbols: DDX9, LKP, NDH II, NDHII, RHA, NDH2

    Protein Interaction Partner: AKAP8L,BRCA1,DDX20,DHX9,GEMIN4,GTF2B,HDLBP,ILF3,JUN,KHDRBS1,MBD2,MGEA5,NXF1,PCNA,POLR2A,PRMT1,PRPF8,RELA,SIP1,SMN2,SMN2,SNRPB,SNRPB2,SRPK1,SSRP1,STAU1,TBP,TOP2A,AKAP8L,ARHGDIA,BRCA1,CNBP,DDX20,GEMIN4,GTF2B,HDLBP,HINFP,JUN,KHDRBS1,LYAR,MBD2,MEPCE,NXF1,PRMT1,RELA,SIP1,SMN1,TBP,TOP2A,XRCC5,XRCC6

    Protein Size: 1279

    Poids moléculaire

    141 kDa

    ID gène

    1660

    NCBI Accession

    NM_001357, NP_001348

    UniProt

    Q08211
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