Dispatched Homolog 1 (DISP1) (Middle Region) Peptide
DISP1
Reactivité: Humain
Hôte: Synthetic
BP, WB
N° du produit ABIN975804
Aperçu rapide pour Dispatched Homolog 1 (DISP1) (Middle Region) Peptide (ABIN975804)
Antigène
DISP1
(Dispatched Homolog 1 (DISP1))
Origine
Humain
Source
Synthetic
Application
Blocking Peptide (BP), Western Blotting (WB)
-
-
Protein Region
- Middle Region
-
Attributs du produit
- This is a synthetic peptide designed for use in combination with anti-DISP1 antibody (Catalog #: ARP50142_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
-
Purification
- Purified
-
-
-
-
Indications d'application
- Each Investigator should determine their own optimal working dilution for specific applications.
-
Restrictions
- For Research Use only
-
-
-
Format
- Lyophilized
-
Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
-
Concentration
- 1 mg/mL
-
Buffer
- Final peptide concentration is 1 mg/mL in PBS.
-
Conseil sur la manipulation
- Avoid repeated freeze-thaw cycles.
-
Stock
- -20 °C
-
Stockage commentaire
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
-
-
- DISP1 (Dispatched Homolog 1 (DISP1))
-
Sujet
-
DISP1 functions in hedgehog (Hh) signaling. Regulates the release and extracellular accumulation of cholesterol-modified hedgehog proteins and is hence required for effective production of the Hh signal.The pattern of cellular proliferation and differentiation that leads to normal development of embryonic structures often depends upon the localized production of secreted protein signals. Cells surrounding the source of a particular signal respond in a graded manner according to the effective concentration of the signal, and this response produces the pattern of cell types constituting the mature structure. A novel segment-polarity gene known as dispatched has been identified in Drosophila and its protein product is required for normal Hedgehog (Hh) signaling. This gene is one of two human homologs of Drosophila dispatched and, based on sequence identity to its mouse counterpart, the encoded protein may play an essential role in Hh patterning activities in the early embryo.
Alias Symbols: DISPA, DKFZP434I0428, FLJ43740, MGC104180, MGC13130, MGC16796
Protein Size: 1524 -
Poids moléculaire
- 171 kDa
-
ID gène
- 84976
-
NCBI Accession
- NM_032890, NP_116279
-
UniProt
- Q96F81
Antigène
-
Vous êtes ici:
