Dickkopf 2 Homolog (DKK2) (Middle Region) Peptide
DKK2
Reactivité: Souris
Hôte: Synthetic
BP, WB
N° du produit ABIN975816
Aperçu rapide pour Dickkopf 2 Homolog (DKK2) (Middle Region) Peptide (ABIN975816)
Antigène
DKK2
(Dickkopf 2 Homolog (DKK2))
Origine
Souris
Source
Synthetic
Application
Blocking Peptide (BP), Western Blotting (WB)
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Protein Region
- Middle Region
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Séquence
- NGICIPVTES ILTPHIPALD GTRHRDRNHG HYSNHDLGWQ NLGRPHSKMP
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Attributs du produit
- This is a synthetic peptide designed for use in combination with anti-Dkk2 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Purification
- Purified
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Dickkopf 2 Homolog (DKK2) peptide
DKK2 Reactivité: Humain, Souris, Boeuf (Vache), Chien, Rat Hôte: Synthetic BP, Imm
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Indications d'application
- Each Investigator should determine their own optimal working dilution for specific applications.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Concentration
- 1 mg/mL
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Buffer
- Final peptide concentration is 1 mg/mL in PBS.
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Conseil sur la manipulation
- Avoid repeated freeze-thaw cycles.
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Stock
- -20 °C
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Stockage commentaire
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- DKK2 (Dickkopf 2 Homolog (DKK2))
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Sujet
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Dkk2 antagonizes canonical Wnt signaling by inhibiting LRP5/6 interaction with Wnt and by forming a ternary complex with the transmembrane protein KREMEN that promotes internalization of LRP5/6. DKKs play an important role in vertebrate development, where they locally inhibit Wnt regulated processes such as antero-posterior axial patterning, limb development, somitogenesis and eye formation. In the adult, Dkks are implicated in bone formation and bone disease, cancer and Alzheimer's disease.
Alias Symbols: -
Protein Size: 259 -
Poids moléculaire
- 28 kDa
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ID gène
- 56811
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NCBI Accession
- NM_020265, NP_064661
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UniProt
- Q9QYZ8
Antigène
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