Dickkopf 2 Homolog (DKK2) (Middle Region) Peptide
DKK2
Reactivité: Souris
Hôte: Synthetic
BP, WB
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- Antigène Tous les produits DKK2
- DKK2 (Dickkopf 2 Homolog (DKK2))
- Protein Region
- Middle Region
- Origine
- Souris
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB)
- Séquence
- NGICIPVTES ILTPHIPALD GTRHRDRNHG HYSNHDLGWQ NLGRPHSKMP
- Attributs du produit
- This is a synthetic peptide designed for use in combination with anti-Dkk2 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- Purification
- Purified
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Dickkopf 2 Homolog (DKK2) peptide
DKK2 Reactivité: Humain, Souris, Boeuf (Vache), Chien, Rat Hôte: Synthetic BP, Imm
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- Indications d'application
- Each Investigator should determine their own optimal working dilution for specific applications.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Concentration
- 1 mg/mL
- Buffer
- Final peptide concentration is 1 mg/mL in PBS.
- Conseil sur la manipulation
- Avoid repeated freeze-thaw cycles.
- Stock
- -20 °C
- Stockage commentaire
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Antigène
- DKK2 (Dickkopf 2 Homolog (DKK2))
- Synonymes
- DKK-2 Peptide, Dkk4 Peptide, zgc:171574 Peptide, dickkopf WNT signaling pathway inhibitor 2 Peptide, DKK2 Peptide, Dkk2 Peptide, dkk2 Peptide
- Sujet
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Dkk2 antagonizes canonical Wnt signaling by inhibiting LRP5/6 interaction with Wnt and by forming a ternary complex with the transmembrane protein KREMEN that promotes internalization of LRP5/6. DKKs play an important role in vertebrate development, where they locally inhibit Wnt regulated processes such as antero-posterior axial patterning, limb development, somitogenesis and eye formation. In the adult, Dkks are implicated in bone formation and bone disease, cancer and Alzheimer's disease.
Alias Symbols: -
Protein Size: 259 - Poids moléculaire
- 28 kDa
- ID gène
- 56811
- NCBI Accession
- NM_020265, NP_064661
- UniProt
- Q9QYZ8
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