Deleted in Malignant Brain Tumors 1 (DMBT1) (N-Term) Peptide
DMBT1
Reactivité: Humain
Hôte: Synthetic
BP, WB
N° du produit ABIN975861
150,78 €
Plus frais de livraison 40,00 € et TVA
100 μg
Destination:
France
Envoi sous 15 à 22 jours ouvrables
Aperçu rapide pour Deleted in Malignant Brain Tumors 1 (DMBT1) (N-Term) Peptide (ABIN975861)
Antigène
DMBT1
(Deleted in Malignant Brain Tumors 1 (DMBT1))
Origine
Humain
Source
Synthetic
Application
Blocking Peptide (BP), Western Blotting (WB)
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Protein Region
- N-Term
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Séquence
- SWSTPSPDTL PTITLPASTV GSESSLALRL VNGGDRCQGR VEVLYRGSWG
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Attributs du produit
- This is a synthetic peptide designed for use in combination with anti-DMBT1 Antibody(ARP42352_P050),. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Purification
- Purified
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Indications d'application
- Each Investigator should determine their own optimal working dilution for specific applications.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Concentration
- 1 mg/mL
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Buffer
- Final peptide concentration is 1 mg/mL in PBS.
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Conseil sur la manipulation
- Avoid repeated freeze-thaw cycles.
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Stock
- -20 °C
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Stockage commentaire
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- DMBT1 (Deleted in Malignant Brain Tumors 1 (DMBT1))
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Sujet
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Loss of sequences from human chromosome 10q has been associated with the progression of human cancers. The gene DMBT1 was originally isolated based on its deletion in a medulloblastoma cell line. DMBT1 is expressed with transcripts of 6.0, 7.5, and 8.0 kb in fetal lung and with one transcript of 8.0 kb in adult lung, although the 7.5 kb transcript has not been characterized. The DMBT1 protein is a glycoprotein containing multiple scavenger receptor cysteine-rich (SRCR) domains separated by SRCR-interspersed domains (SID). Transcript variant 2 (8.0 kb) has been shown to bind surfactant protein D independently of carbohydrate recognition. This indicates that DMBT1 may not be a classical tumor supressor gene, but rather play a role in the interaction of tumor cells and the immune system.
Alias Symbols: GP340, MGC164738, muclin
Protein Interaction Partner: SFTPA1,SFTPD,SFTPA1,SFTPD
Protein Size: 2413 -
Poids moléculaire
- 258 kDa
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ID gène
- 1755
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NCBI Accession
- NM_007329, NP_015568
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UniProt
- Q9UGM3
Antigène
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