Dishevelled Segment Polarity Protein 1 (DVL1) Peptide
DVL1
Reactivité: Humain
Hôte: Synthetic
BP, WB
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- Antigène Tous les produits DVL1
- DVL1 (Dishevelled Segment Polarity Protein 1 (DVL1))
- Origine
- Humain
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB)
- Attributs du produit
- This is a synthetic peptide designed for use in combination with anti-DVL1 antibody (Catalog #: ARP32101_T100). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- Purification
- Purified
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- Indications d'application
- Each Investigator should determine their own optimal working dilution for specific applications.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Concentration
- 1 mg/mL
- Buffer
- Final peptide concentration is 1 mg/mL in PBS.
- Conseil sur la manipulation
- Avoid repeated freeze-thaw cycles.
- Stock
- -20 °C
- Stockage commentaire
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Antigène
- DVL1 (Dishevelled Segment Polarity Protein 1 (DVL1))
- Synonymes
- DVL Peptide, DVL1L1 Peptide, DVL1P1 Peptide, Dvl Peptide, mKIAA4029 Peptide, dvl-1 Peptide, DSH Peptide, DVL-1 Peptide, dvl1 Peptide, dvl2l Peptide, Xdsh Peptide, dsh1 Peptide, dishevelled segment polarity protein 1 Peptide, dishevelled, dsh homolog 1 (Drosophila) Peptide, microRNA 6808 Peptide, dishevelled segment polarity protein 1b Peptide, dishevelled segment polarity protein 1 L homeolog Peptide, DVL1 Peptide, Dvl1 Peptide, MIR6808 Peptide, dvl1b Peptide, dvl1.L Peptide
- Sujet
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DVL1 is a cytoplasmic phosphoprotein that regulates cell proliferation, acting as a transducer molecule for developmental processes, including segmentation and neuroblast specification. DVL1 gene is a candidate for neuroblastomatous transformation. The Schwartz-Jampel syndrome and Charcot-Marie-Tooth disease type 2A have been mapped to the same region as DVL1 gene. The phenotypes of these diseases may be consistent with defects which might be expected from aberrant expression of a DVL gene during development.DVL1, the human homolog of the Drosophila dishevelled gene (dsh) encodes a cytoplasmic phosphoprotein that regulates cell proliferation, acting as a transducer molecule for developmental processes, including segmentation and neuroblast specification. DVL1 is a candidate gene for neuroblastomatous transformation. The Schwartz-Jampel syndrome and Charcot-Marie-Tooth disease type 2A have been mapped to the same region as DVL1. The phenotypes of these diseases may be consistent with defects which might be expected from aberrant expression of a DVL gene during development. Three transcript variants encoding three different isoforms have been found for this gene.
Alias Symbols: DVL, MGC54245, DVL1L1
Protein Interaction Partner: ARRB1,AXIN1,BRD7,CCDC88C,CSNK1D,CSNK1E,CSNK2A1,CTNNB1,CXXC4,DAAM1,DVL1,DVL3,DYNLT1,EPS8,FRAT1,HDHD2,HECW1,PPM1A,RAC1,SMAD2,SMAD3,SMAD4,SMAD7,USP13,VANGL1,VANGL2,ARRB1,ATN1,AXIN1,Axin1,CSNK1D,CSNK1E,CSNK2A1,CTNNB1,DAB2,DVL1,DVL3,EPS8,FRAT1,HECW1,SMAD1,SMAD2,SMAD3,SMAD4,SMAD7,USP13
Protein Size: 670 - Poids moléculaire
- 73 kDa
- ID gène
- 1855
- NCBI Accession
- NM_004421, NP_004412
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