Dual-Specificity tyrosine-(Y)-phosphorylation Regulated Kinase 3 (DYRK3) (N-Term) Peptide
Aperçu rapide pour Dual-Specificity tyrosine-(Y)-phosphorylation Regulated Kinase 3 (DYRK3) (N-Term) Peptide (ABIN976065)
Antigène
Origine
Source
Application
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Protein Region
- N-Term
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Séquence
- GDHTQHFLDG GEMKVEQLFQ EFGNRKSNTI QSDGISDSEK CSPTVSQGKS
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Attributs du produit
- This is a synthetic peptide designed for use in combination with anti-DYRK3 Antibody(ARP30648_P050),. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Purification
- Purified
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Indications d'application
- Each Investigator should determine their own optimal working dilution for specific applications.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Concentration
- 1 mg/mL
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Buffer
- Final peptide concentration is 1 mg/mL in PBS.
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Conseil sur la manipulation
- Avoid repeated freeze-thaw cycles.
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Stock
- -20 °C
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Stockage commentaire
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- DYRK3 (Dual-Specificity tyrosine-(Y)-phosphorylation Regulated Kinase 3 (DYRK3))
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Sujet
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This gene product belongs to the DYRK family of dual-specificity protein kinases that catalyze autophosphorylation on serine/threonine and tyrosine residues. The members of this family share structural similarity, however, differ in their substrate specificity, suggesting their involvement in different cellular functions. The encoded protein has been shown to autophosphorylate on tyrosine residue and catalyze phosphorylation of histones H3 and H2B in vitro. Alternatively spliced transcript variants encoding different isoforms have been identified.
Alias Symbols: DYRK5, RED, REDK, hYAK3-2
Protein Size: 588 -
Poids moléculaire
- 66 kDa
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ID gène
- 8444
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NCBI Accession
- NM_003582, NP_003573
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UniProt
- O43781
Antigène
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