Vacuolar-sorting Protein SNF8 (SNF8) Peptide
SNF8
Reactivité: Humain
Hôte: Synthetic
BP, WB, IHC
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- Antigène Tous les produits SNF8
- SNF8 (Vacuolar-sorting Protein SNF8 (SNF8))
- Origine
- Humain
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB), Immunohistochemistry (IHC)
- Attributs du produit
- This is a synthetic peptide designed for use in combination with anti-SNF8 antibody (Catalog #: ARP31531_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- Purification
- Purified
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- Indications d'application
- Each Investigator should determine their own optimal working dilution for specific applications.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Concentration
- 1 mg/mL
- Buffer
- Final peptide concentration is 1 mg/mL in PBS.
- Conseil sur la manipulation
- Avoid repeated freeze-thaw cycles.
- Stock
- -20 °C
- Stockage commentaire
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Antigène
- SNF8 (Vacuolar-sorting Protein SNF8 (SNF8))
- Synonymes
- d11moh34 Peptide, vps22 Peptide, Dot3 Peptide, EAP30 Peptide, VPS22 Peptide, D11moh34 Peptide, RGD1310144 Peptide, D11Moh34 Peptide, D11MOH34 Peptide, zgc:101578 Peptide, SNF8, ESCRT-II complex subunit Peptide, eap30 subunit of ell complex, putative Peptide, EAP30 subunit of ELL complex Peptide, SNF8, ESCRT-II complex subunit S homeolog Peptide, SNF8, ESCRT-II complex subunit, homolog (S. cerevisiae) Peptide, snf8 Peptide, TA17290 Peptide, TVAG_107410 Peptide, Bm1_05145 Peptide, SNF8 Peptide, Snf8 Peptide, snf8.S Peptide
- Sujet
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ELL encodes an RNA polymerase II transcription factor that undergoes frequent translocation in acute myeloid leukemia (AML). In addition to its elongation activity, ELL contains a novel type of RNA polymerase II interaction domain that is capable of repressing polymerase activity in promoter-specific transcription. EAP30 is a subunit of the ELL complex. EAP30 can interact with ELL and derepress ELL's inhibitory activity in vitro.SNF8, VPS25 (MIM 610907), and VPS36 (MIM 610903) form ESCRT-II (endosomal sorting complex required for transport II), a complex involved in endocytosis of ubiquitinated membrane proteins. SNF8, VPS25, and VPS36 are also associated in a multiprotein complex with RNA polymerase II elongation factor (ELL, MIM 600284) (Slagsvold et al., 2005 [PubMed 15755741], Kamura et al., 2001 [PubMed 11278625]).[supplied by OMIM].
Alias Symbols: Dot3, EAP30, VPS22
Protein Interaction Partner: CHMP6,DVL2,ELL,NIF3L1,TSG101,VPS25,VPS36,DVL2,ELL,NIF3L1,VPS25
Protein Size: 258 - Poids moléculaire
- 29 kDa
- ID gène
- 11267
- NCBI Accession
- NM_007241, NP_009172
- UniProt
- Q96H20
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