Ectodysplasin A Receptor (EDAR) Peptide
EDAR
Reactivité: Humain
Hôte: Synthetic
BP, WB
N° du produit ABIN976123
Aperçu rapide pour Ectodysplasin A Receptor (EDAR) Peptide (ABIN976123)
Antigène
EDAR
(Ectodysplasin A Receptor (EDAR))
Origine
Humain
Source
Synthetic
Application
Blocking Peptide (BP), Western Blotting (WB)
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Attributs du produit
- This is a synthetic peptide designed for use in combination with anti-EDAR antibody (Catalog #: ARP49706_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Purification
- Purified
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Indications d'application
- Each Investigator should determine their own optimal working dilution for specific applications.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Concentration
- 1 mg/mL
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Buffer
- Final peptide concentration is 1 mg/mL in PBS.
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Conseil sur la manipulation
- Avoid repeated freeze-thaw cycles.
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Stock
- -20 °C
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Stockage commentaire
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- EDAR (Ectodysplasin A Receptor (EDAR))
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Sujet
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EDAR is a member of the tumor necrosis factor receptor family. It is a receptor for the soluble ligand ectodysplasin A, and can activate the nuclear factor-kappaB, JNK, and caspase-independent cell death pathways. It is required for the development of hair, teeth, and other ectodermal derivatives. Mutations in the gene encoding EDAR result in autosomal dominant and recessive forms of hypohidrotic ectodermal dysplasia.This gene encodes a member of the tumor necrosis factor receptor family. The encoded transmembrane protein is a receptor for the soluble ligand ectodysplasin A, and can activate the nuclear factor-kappaB, JNK, and caspase-independent cell death pathways. It is required for the development of hair, teeth, and other ectodermal derivatives. Mutations in this gene result in autosomal dominant and recessive forms of hypohidrotic ectodermal dysplasia. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: DL, ED1R, ED3, ED5, EDA-A1R, EDA1R, EDA3, HRM1
Protein Interaction Partner: EDA,EDARADD,MAP3K14,TRAF1,TRAF2,TRAF3,EDA,EDARADD
Protein Size: 448 -
Poids moléculaire
- 48 kDa
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ID gène
- 10913
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NCBI Accession
- NM_022336, NP_071731
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UniProt
- Q9UNE0
Antigène
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