Epidermal Growth Factor Receptor (EGFR) (Middle Region) Peptide
EGFR
Reactivité: Humain
Hôte: Synthetic
BP, WB
N° du produit ABIN976174
Aperçu rapide pour Epidermal Growth Factor Receptor (EGFR) (Middle Region) Peptide (ABIN976174)
Antigène
EGFR
(Epidermal Growth Factor Receptor (EGFR))
Origine
Humain
Source
Synthetic
Application
Blocking Peptide (BP), Western Blotting (WB)
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Protein Region
- Middle Region
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Séquence
- VTDHGSCVRA CGADSYEMEE DGVRKCKKCE GPCRKVCNGI GIGEFKDSLS
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Attributs du produit
- This is a synthetic peptide designed for use in combination with anti-EGFR Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Purification
- Purified
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Indications d'application
- Each Investigator should determine their own optimal working dilution for specific applications.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Concentration
- 1 mg/mL
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Buffer
- Final peptide concentration is 1 mg/mL in PBS.
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Conseil sur la manipulation
- Avoid repeated freeze-thaw cycles.
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Stock
- -20 °C
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Stockage commentaire
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- EGFR (Epidermal Growth Factor Receptor (EGFR))
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Sujet
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The protein encoded by this gene is a transmembrane glycoprotein that is a member of the protein kinase superfamily. This protein is a receptor for members of the epidermal growth factor family. EGFR is a cell surface protein that binds to epidermal growth factor. Binding of the protein to a ligand induces receptor dimerization and tyrosine autophosphorylation and leads to cell proliferation. Mutations in this gene are associated with lung cancer. Multiple alternatively spliced transcript variants that encode different protein isoforms have been found for this gene.
Alias Symbols: ERBB, ERBB1, HER1, PIG61, mENA
Protein Interaction Partner: CALM1,CD44,CDH1,EGF,EGFR,ERBB2,GRB2,HSP90AA1,MUC1,PAK1,PIK3R1,PIK3R2,PLCG1,PLD2,RASA1,SHC1,SHC1,SHC1,STAT3,VAV2,ACTA1,ADRBK1,AGTR1,ALCAM,AMH,ANXA1,AR,AREG,ARF4,ATP1A1,ATP1B1,ATP5C1,BTC,CALM1,CALM3,CALM3,CAMK2A,CAMK2G,CAMLG,CASP1,CAV1,CAV2,CAV3,CBL,CBLB,CB
Protein Size: 628 -
Poids moléculaire
- 69 kDa
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ID gène
- 1956
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NCBI Accession
- NM_201282, NP_958439
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UniProt
- P00533
Antigène
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