Early Growth Response 4 (EGR4) Peptide
EGR4
Reactivité: Humain
Hôte: Synthetic
BP, WB
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- Antigène Tous les produits EGR4
- EGR4 (Early Growth Response 4 (EGR4))
- Origine
- Humain
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB)
- Attributs du produit
- This is a synthetic peptide designed for use in combination with anti-EGR4 antibody (Catalog #: ARP38090_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- Purification
- Purified
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Early Growth Response 4 (EGR4) peptide
EGR4 Reactivité: Humain Hôte: Synthetic BP, Imm
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- Indications d'application
- Each Investigator should determine their own optimal working dilution for specific applications.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Concentration
- 1 mg/mL
- Buffer
- Final peptide concentration is 1 mg/mL in PBS.
- Conseil sur la manipulation
- Avoid repeated freeze-thaw cycles.
- Stock
- -20 °C
- Stockage commentaire
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Antigène
- EGR4 (Early Growth Response 4 (EGR4))
- Synonymes
- EGR4 Peptide, NGFI-C Peptide, NGFIC Peptide, PAT133 Peptide, NGF1-C Peptide, pAT133 Peptide, Egr4l1 Peptide, early growth response 4 Peptide, EGR4 Peptide, Egr4 Peptide
- Sujet
-
The nerve growth factor-induced clone C (NGFI-C/EGR4) gene is a zinc-finger transcription factor that is rapidly induced by nerve growth factor in rat pheochromocytoma PC12 cells and by seizure in brain. NGFI-C/EGR4 is closely related to the previously described early response genes, nerve growth factor-induced clone A (NGFI-A or EGR1), EGR2, and EGR3. These four early response (immediate early) proteins all contain very similar zinc-finger DNA binding domains and five highly homologous subdomains. EGR-4 functionally cooperate with NFAT proteins and induce expression of IL-2 and TNFalpha. Early growth response proteins (EGR) and nuclear factors of activated T cells (NFAT) form heterodimers and regulate proinflammatory cytokine gene expression.
Alias Symbols: NGFIC, NGFI-C, PAT133
Protein Interaction Partner: NFATC2
Protein Size: 486 - Poids moléculaire
- 51 kDa
- ID gène
- 1961
- NCBI Accession
- NM_001965, NP_001956
- UniProt
- Q05215
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