Eukaryotic Translation Initiation Factor 3 Subunit E (EIF3E) (N-Term) Peptide
EIF3E
Reactivité: Humain
Hôte: Synthetic
BP, WB, IHC
N° du produit ABIN976223
Aperçu rapide pour Eukaryotic Translation Initiation Factor 3 Subunit E (EIF3E) (N-Term) Peptide (ABIN976223)
Antigène
EIF3E
(Eukaryotic Translation Initiation Factor 3 Subunit E (EIF3E))
Origine
Humain
Source
Synthetic
Application
Blocking Peptide (BP), Western Blotting (WB), Immunohistochemistry (IHC)
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Protein Region
- N-Term
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Attributs du produit
- This is a synthetic peptide designed for use in combination with anti-EIF3E antibody (Catalog #: ARP48175_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Purification
- Purified
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Indications d'application
- Each Investigator should determine their own optimal working dilution for specific applications.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Concentration
- 1 mg/mL
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Buffer
- Final peptide concentration is 1 mg/mL in PBS.
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Conseil sur la manipulation
- Avoid repeated freeze-thaw cycles.
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Stock
- -20 °C
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Stockage commentaire
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- EIF3E (Eukaryotic Translation Initiation Factor 3 Subunit E (EIF3E))
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Sujet
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EIF3E belongs to the eIF-3 subunit E family.It is a component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is required for several steps in the initiation of protein synthesis. EIF3E is required for nonsense-mediated mRNA decay (NMD), It may act in conjunction with UPF2 to divert mRNAs from translation to the NMD pathway. The protein may interact with MCM7 and EPAS1 and regulate the proteasome-mediated degradation of these proteins.
Alias Symbols: EIF3-P48, EIF3S6, INT6, eIF3-p46
Protein Interaction Partner: tax,BAT2,COPS6,COPS7A,COPS7B,COPS8,DDX24,EIF3C,EIF3L,EIF4ENIF1,EPAS1,GPAA1,GPBP1L1,HAP1,IFIT1,NDRG1,NSF,RUNDC3A,SMAD9,TRIM27,BAT2,CNTF,COPS6,CSN3,DDX24,EIF1B,EIF3A,EIF3F,EIF3H,EIF3L,GPAA1,GPBP1L1,HAP1,IFIT1,MAGED1,NSF,RGS2,RUNDC3A,SAP18,TRIM27,USP20
Protein Size: 445 -
Poids moléculaire
- 52 kDa
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ID gène
- 3646
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NCBI Accession
- NM_001568, NP_001559
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UniProt
- P60228
Antigène
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