Erythropoietin Receptor (EPOR) (N-Term) Peptide
EPOR
Reactivité: Humain
Hôte: Synthetic
BP, WB
N° du produit ABIN976391
Aperçu rapide pour Erythropoietin Receptor (EPOR) (N-Term) Peptide (ABIN976391)
Antigène
EPOR
(Erythropoietin Receptor (EPOR))
Origine
Humain
Source
Synthetic
Application
Blocking Peptide (BP), Western Blotting (WB)
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Protein Region
- N-Term
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Attributs du produit
- This is a synthetic peptide designed for use in combination with anti-EPOR antibody (Catalog #: ARP44216_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Purification
- Purified
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Indications d'application
- Each Investigator should determine their own optimal working dilution for specific applications.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Concentration
- 1 mg/mL
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Buffer
- Final peptide concentration is 1 mg/mL in PBS.
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Conseil sur la manipulation
- Avoid repeated freeze-thaw cycles.
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Stock
- -20 °C
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Stockage commentaire
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- EPOR (Erythropoietin Receptor (EPOR))
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Sujet
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The erythropoietin receptor is a member of the cytokine receptor family. Upon erythropoietin binding, the erythropoietin receptor activates Jak2 tyrosine kinase which activates different intracellular pathways including: Ras/MAP kinase, phosphatidylinositol 3-kinase and STAT transcription factors. The stimulated erythropoietin receptor appears to have a role in erythroid cell survival. Defects in the erythropoietin receptor may produce erythroleukemia and familial erythrocytosis.The erythropoietin receptor is a member of the cytokine receptor family. Upon erythropoietin binding, the erythropoietin receptor activates Jak2 tyrosine kinase which activates different intracellular pathways including: Ras/MAP kinase, phosphatidylinositol 3-kinase and STAT transcription factors. The stimulated erythropoietin receptor appears to have a role in erythroid cell survival. Defects in the erythropoietin receptor may produce erythroleukemia and familial erythrocytosis. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: MGC138358, EPO-R
Protein Interaction Partner: EPO,EPO,EPOR,GNB2L1,ATXN2L,CBL,CISH,CRKL,CSF2RB,EPO,EPOR,GAB1,GAB2,GNAI1,GNB2L1,GRAP,GRB2,INPP5D,IRS2,JAK2,KIT,KITLG,KLK3,LYN,MAPK1,MAPK3,MST1R,PIK3R1,PLCG1,PLCG2,PTPN11,PTPN6,SH2B2,SHC1,SOCS2,SOCS3,STAT5A,STAT5B,SYK,VAV1,ATXN2L,BTRC,CISH,CRKL,EPO,GNAI1,GNB2L1,GRAP,GRB2,IRS2,JAK2,LYN,PIK3R1,PTPN11,PTPN6,SHC1,SOCS2,SOCS3,STAT5A,SYK,SYP,VAV1
Protein Size: 508 -
Poids moléculaire
- 53 kDa
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ID gène
- 2057
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NCBI Accession
- NM_000121, NP_000112
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UniProt
- P19235
Antigène
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