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Epidermal Growth Factor Receptor Pathway Substrate 15 (EPS15) Peptide

EPS15 Reactivité: Humain Hôte: Synthetic BP, WB
N° du produit ABIN976395
  • Antigène Tous les produits EPS15
    EPS15 (Epidermal Growth Factor Receptor Pathway Substrate 15 (EPS15))
    Origine
    Humain
    Source
    • 2
    Synthetic
    Application
    Blocking Peptide (BP), Western Blotting (WB)
    Attributs du produit
    This is a synthetic peptide designed for use in combination with anti-EPS15 antibody (Catalog #: ARP54601_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
    Purification
    Purified
  • Indications d'application
    Each Investigator should determine their own optimal working dilution for specific applications.
    Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
    Concentration
    1 mg/mL
    Buffer
    Final peptide concentration is 1 mg/mL in PBS.
    Conseil sur la manipulation
    Avoid repeated freeze-thaw cycles.
    Stock
    -20 °C
    Stockage commentaire
    For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
  • Antigène
    EPS15 (Epidermal Growth Factor Receptor Pathway Substrate 15 (EPS15))
    Synonymes
    AF-1P Peptide, AF1P Peptide, MLLT5 Peptide, CG16932 Peptide, Dmel\\CG16932 Peptide, EH1 Peptide, EPS-15 Peptide, Eps15 Peptide, anon-WO0118547.85 Peptide, eps-15 Peptide, eps15 Peptide, i31 Peptide, 2410112D09Rik Peptide, RGD1307641 Peptide, epidermal growth factor receptor pathway substrate 15 Peptide, Epidermal growth factor receptor pathway substrate clone 15 Peptide, hypothetical protein Peptide, EPS15 Peptide, Eps-15 Peptide, eps15 Peptide, Eps15 Peptide, PGTG_06574 Peptide
    Sujet
    EPS15 is a protein that is part of the EGFR pathway. The protein is present at clatherin-coated pits and is involved in receptor-mediated endocytosis of EGF. Notably, this gene is rearranged with the HRX/ALL/MLL gene in acute myelogeneous leukemias.This gene encodes a protein that is part of the EGFR pathway. The protein is present at clatherin-coated pits and is involved in receptor-mediated endocytosis of EGF. Notably, this gene is rearranged with the HRX/ALL/MLL gene in acute myelogeneous leukemias. Alternate transcriptional splice variants of this gene have been observed but have not been thoroughly characterized. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.

    Alias Symbols: AF-1P, AF1P, MLLT5

    Protein Interaction Partner: AGFG1,AGFG2,CDC40,EPN2,EPN2,NUMB,NUMBL,RNF11,SH3BP4,AGFG1,AGFG2,AP2A1,AP2A2,CRK,DNM1,DNM2,EGFR,ELF3,EPN1,EPN2,EPS15,HGS,ITSN1,LAPTM5,MOBKL3,NAGPA,NEDD4,NUMB,NUMBL,REPS2,RNF11,SNAP91,SPG20,STAM2,STAMBP,STON2,SYNJ1,UBB,UBQLN1,AGFG1,AGFG2,AP2A1,AP2A2,CLINT1,CRK,DNM2,EGFR,EPN1,GRB2,HGS,NAGPA,RAB11FIP2,REPS2,RNF11,SCAMP1,SLC6A3,SNAP91,STAM2,STON2,Synj1,UBE2D1,UBE2D2,UBE2D3,UBE2E1,UBE2H

    Protein Size: 896
    Poids moléculaire
    99 kDa
    ID gène
    2060
    NCBI Accession
    NM_001981, NP_001972
    UniProt
    P42566
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