Coagulation Factor XI (F11) (C-Term) Peptide
F11
Reactivité: Humain
Hôte: Synthetic
BP, WB
N° du produit ABIN976543
Aperçu rapide pour Coagulation Factor XI (F11) (C-Term) Peptide (ABIN976543)
Antigène
Factor XI (F11)
(Coagulation Factor XI (F11))
Origine
Humain
Source
Synthetic
Application
Blocking Peptide (BP), Western Blotting (WB)
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Protein Region
- C-Term
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Séquence
- RHLCGGSIIG NQWILTAAHC FYGVESPKIL RVYSGILNQS EIKEDTSFFG
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Attributs du produit
- This is a synthetic peptide designed for use in combination with anti-F11 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Purification
- Purified
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Indications d'application
- Each Investigator should determine their own optimal working dilution for specific applications.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Concentration
- 1 mg/mL
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Buffer
- Final peptide concentration is 1 mg/mL in PBS.
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Conseil sur la manipulation
- Avoid repeated freeze-thaw cycles.
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Stock
- -20 °C
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Stockage commentaire
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Factor XI (F11) (Coagulation Factor XI (F11))
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Sujet
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This gene encodes coagulation factor XI of the blood coagulation cascade. This protein is present in plasma as a zymogen, which is a unique plasma coagulation enzyme because it exists as a homodimer consisting of two identical polypeptide chains linked by disulfide bonds. During activation of the plasma factor XI, an internal peptide bond is cleaved by factor XIIa (or XII) in each of the two chains, resulting in activated factor XIa, a serine protease composed of two heavy and two light chains held together by disulfide bonds. This activated plasma factor XI triggers the middle phase of the intrisic pathway of blood coagulation by activating factor IX. Defects in this factor lead to Rosenthal syndrome, a blood coagulation abnormality.
Alias Symbols: FXI, MGC141891
Protein Interaction Partner: F11,F2,HGF,KNG1,SERPINA5,SERPINF2,TFPI2,KNG1,SERPINA5
Protein Size: 625 -
Poids moléculaire
- 70 kDa
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ID gène
- 2160
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NCBI Accession
- NM_000128, NP_000119
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UniProt
- P03951
Antigène
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