Coagulation Factor II (thrombin) (F2) (Middle Region) Peptide
Aperçu rapide pour Coagulation Factor II (thrombin) (F2) (Middle Region) Peptide (ABIN976548)
Antigène
Origine
Source
Application
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Protein Region
- Middle Region
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Attributs du produit
- This is a synthetic peptide designed for use in combination with anti-F2 antibody (Catalog #: ARP41757_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Purification
- Purified
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Indications d'application
- Each Investigator should determine their own optimal working dilution for specific applications.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Concentration
- 1 mg/mL
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Buffer
- Final peptide concentration is 1 mg/mL in PBS.
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Conseil sur la manipulation
- Avoid repeated freeze-thaw cycles.
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Stock
- -20 °C
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Stockage commentaire
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Prothrombin (F2) (Coagulation Factor II (thrombin) (F2))
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Sujet
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Coagulation factor II is proteolytically cleaved to form thrombin in the first step of the coagulation cascade which ultimately results in the stemming of blood loss. F2 also plays a role in maintaining vascular integrity during development and postnatal life.Coagulation factor II is proteolytically cleaved to form thrombin in the first step of the coagulation cascade which ultimately results in the stemming of blood loss. F2 also plays a role in maintaining vascular integrity during development and postnatal life. Mutations in F2 leads to various forms of thrombosis and dysprothrombinemia. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: PT
Protein Interaction Partner: F2R,AANAT,AKR7A2,AMBP,C6,CPB2,F11,F13A1,F2,F2R,F2RL1,F2RL2,F2RL3,F5,F8,F9,FGA,GGCX,GP1BA,GP5,HGFAC,IGFBP3,IGFBP5,ITGA2B,KNG1,PLAU,PROC,PROS1,PROZ,SERPINA5,SERPINB6,SERPINB8,SERPINC1,SERPIND1,SERPINE1,SERPINE2,SERPING1,SPP1,ST13,THBD,THBS1,CPB2,F5,FGA,ITGA2B,PLAT,SERPINB6,SERPIND1,SERPINE1,SERPING1,THBD,THBS1
Protein Size: 622 -
Poids moléculaire
- 65 kDa
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ID gène
- 2147
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NCBI Accession
- NM_000506, NP_000497
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UniProt
- P00734
Antigène
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