Family with Sequence Similarity 120A (FAM120A) (Middle Region) Peptide
FAM120A
Reactivité: Humain
Hôte: Synthetic
BP, WB
N° du produit ABIN976594
Aperçu rapide pour Family with Sequence Similarity 120A (FAM120A) (Middle Region) Peptide (ABIN976594)
Antigène
FAM120A
(Family with Sequence Similarity 120A (FAM120A))
Origine
Humain
Source
Synthetic
Application
Blocking Peptide (BP), Western Blotting (WB)
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Protein Region
- Middle Region
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Attributs du produit
- This is a synthetic peptide designed for use in combination with anti-FAM120A antibody (Catalog #: ARP55089_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Purification
- Purified
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Indications d'application
- Each Investigator should determine their own optimal working dilution for specific applications.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Concentration
- 1 mg/mL
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Buffer
- Final peptide concentration is 1 mg/mL in PBS.
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Conseil sur la manipulation
- Avoid repeated freeze-thaw cycles.
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Stock
- -20 °C
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Stockage commentaire
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- FAM120A (Family with Sequence Similarity 120A (FAM120A))
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Sujet
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FAM120A may participate in mRNA transport in the cytoplasm. FAM120A is the critical component of the oxidative stress-induced survival signaling. It activates src family kinases and acts as a scaffolding protein enabling src family kinases to phosphorylate and activate PI3-kinase. FAM120A binds RNA and promotes the secretion of IGF-II. It may play a pivotal role in the progression of scirrhous-type gastric cancer by supporting cancer cell survival in environments with various oxidative stresses.
Alias Symbols: C9orf10, DNAPTP1, DNAPTP5, MGC111527, MGC133257, OSSA
Protein Size: 1118 -
Poids moléculaire
- 122 kDa
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ID gène
- 23196
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NCBI Accession
- NM_014612, NP_055427
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UniProt
- Q9NZB2
Antigène
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