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F-Box and Leucine-Rich Repeat Protein 3 (FBXL3) (C-Term) Peptide

FBXL3 Reactivité: Humain, Souris Hôte: Synthetic BP, WB
N° du produit ABIN976718

Aperçu rapide pour F-Box and Leucine-Rich Repeat Protein 3 (FBXL3) (C-Term) Peptide (ABIN976718)

Antigène

FBXL3 (F-Box and Leucine-Rich Repeat Protein 3 (FBXL3))

Origine

Humain, Souris

Source

  • 4
Synthetic

Application

Blocking Peptide (BP), Western Blotting (WB)
  • Protein Region

    C-Term

    Séquence

    ELLLALSSEK HVRLEHLRID VVSENPGQTH FHTIQKSSWD AFIKHSPKVN

    Attributs du produit

    This is a synthetic peptide designed for use in combination with anti-Fbxl3 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.

    Purification

    Purified
  • Indications d'application

    Each Investigator should determine their own optimal working dilution for specific applications.

    Restrictions

    For Research Use only
  • Format

    Lyophilized

    Reconstitution

    Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.

    Concentration

    1 mg/mL

    Buffer

    Final peptide concentration is 1 mg/mL in PBS.

    Conseil sur la manipulation

    Avoid repeated freeze-thaw cycles.

    Stock

    -20 °C

    Stockage commentaire

    For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
  • Antigène

    FBXL3 (F-Box and Leucine-Rich Repeat Protein 3 (FBXL3))

    Sujet

    Fbxl3 is a substrate-recognition component of some SCF (SKP1-CUL1-F-box protein)-type E3 ubiquitin ligase complex involved in circadian clock function. The SCF(FBXL3) complex acts by mediating ubiquitination and subsequent degradation of CRY1 and CRY2. Recruiter of target protein that may recognize and bind to some phosphorylated proteins and promotes their ubiquitination and degradation.

    Alias Symbols: AU041772, AW212966, FBK, Fbl3a, Fbxl3a, Ovtm

    Protein Size: 428

    Poids moléculaire

    49 kDa

    ID gène

    50789

    NCBI Accession

    NM_015822, NP_056637

    UniProt

    Q8C4V4
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