F-Box and Leucine-Rich Repeat Protein 3 (FBXL3) (C-Term) Peptide
Aperçu rapide pour F-Box and Leucine-Rich Repeat Protein 3 (FBXL3) (C-Term) Peptide (ABIN976718)
Antigène
Origine
Source
Application
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Protein Region
- C-Term
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Séquence
- ELLLALSSEK HVRLEHLRID VVSENPGQTH FHTIQKSSWD AFIKHSPKVN
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Attributs du produit
- This is a synthetic peptide designed for use in combination with anti-Fbxl3 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Purification
- Purified
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Indications d'application
- Each Investigator should determine their own optimal working dilution for specific applications.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Concentration
- 1 mg/mL
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Buffer
- Final peptide concentration is 1 mg/mL in PBS.
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Conseil sur la manipulation
- Avoid repeated freeze-thaw cycles.
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Stock
- -20 °C
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Stockage commentaire
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- FBXL3 (F-Box and Leucine-Rich Repeat Protein 3 (FBXL3))
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Sujet
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Fbxl3 is a substrate-recognition component of some SCF (SKP1-CUL1-F-box protein)-type E3 ubiquitin ligase complex involved in circadian clock function. The SCF(FBXL3) complex acts by mediating ubiquitination and subsequent degradation of CRY1 and CRY2. Recruiter of target protein that may recognize and bind to some phosphorylated proteins and promotes their ubiquitination and degradation.
Alias Symbols: AU041772, AW212966, FBK, Fbl3a, Fbxl3a, Ovtm
Protein Size: 428 -
Poids moléculaire
- 49 kDa
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ID gène
- 50789
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NCBI Accession
- NM_015822, NP_056637
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UniProt
- Q8C4V4
Antigène
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