F-Box and WD Repeat Domain Containing 10 (FBXW10) (Middle Region) Peptide
FBXW10
Reactivité: Humain
Hôte: Synthetic
BP, WB
N° du produit ABIN976765
Aperçu rapide pour F-Box and WD Repeat Domain Containing 10 (FBXW10) (Middle Region) Peptide (ABIN976765)
Antigène
FBXW10
(F-Box and WD Repeat Domain Containing 10 (FBXW10))
Origine
Humain
Source
Synthetic
Application
Blocking Peptide (BP), Western Blotting (WB)
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Protein Region
- Middle Region
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Attributs du produit
- This is a synthetic peptide designed for use in combination with anti-FBXW10 antibody (Catalog #: ARP52421_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Purification
- Purified
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Indications d'application
- Each Investigator should determine their own optimal working dilution for specific applications.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Concentration
- 1 mg/mL
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Buffer
- Final peptide concentration is 1 mg/mL in PBS.
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Conseil sur la manipulation
- Avoid repeated freeze-thaw cycles.
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Stock
- -20 °C
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Stockage commentaire
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- FBXW10 (F-Box and WD Repeat Domain Containing 10 (FBXW10))
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Sujet
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Members of the F-box protein family, such as FBXW10, are characterized by an approximately 40-amino acid F-box motif. SCF complexes, formed by SKP1 (MIM 601434), cullin (see CUL1, MIM 603134), and F-box proteins, act as protein-ubiquitin ligases. F-box proteins interact with SKP1 through the F box, and they interact with ubiquitination targets through other protein interaction domains. Western blots using two different antibodies against two unique regions of this protein target confirm the same apparent molecular weight in our tests.Members of the F-box protein family, such as FBXW10, are characterized by an approximately 40-amino acid F-box motif. SCF complexes, formed by SKP1 (MIM 601434), cullin (see CUL1, MIM 603134), and F-box proteins, act as protein-ubiquitin ligases. F-box proteins interact with SKP1 through the F box, and they interact with ubiquitination targets through other protein interaction domains (Jin et al., 2004 [PubMed 15520277]).[supplied by OMIM].
Alias Symbols: Fbw10, HREP, SM25H2, SM2SH2
Protein Size: 1051 -
Poids moléculaire
- 120 kDa
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ID gène
- 10517
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NCBI Accession
- NM_031456, NP_113644
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UniProt
- Q5XX13
Antigène
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