Fibrinogen alpha Chain (FGA) Peptide
FGA
Reactivité: Humain
Hôte: Synthetic
BP, WB, IHC
N° du produit ABIN976820
Aperçu rapide pour Fibrinogen alpha Chain (FGA) Peptide (ABIN976820)
Antigène
FGA
(Fibrinogen alpha Chain (FGA))
Origine
Humain
Source
Synthetic
Application
Blocking Peptide (BP), Western Blotting (WB), Immunohistochemistry (IHC)
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Attributs du produit
- This is a synthetic peptide designed for use in combination with anti-FGA antibody (Catalog #: ARP41758_T100). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Purification
- Purified
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Indications d'application
- Each Investigator should determine their own optimal working dilution for specific applications.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Concentration
- 1 mg/mL
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Buffer
- Final peptide concentration is 1 mg/mL in PBS.
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Conseil sur la manipulation
- Avoid repeated freeze-thaw cycles.
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Stock
- -20 °C
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Stockage commentaire
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- FGA (Fibrinogen alpha Chain (FGA))
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Sujet
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FGA is the alpha component of fibrinogen, a blood-borne glycoprotein comprised of three pairs of nonidentical polypeptide chains. Following vascular injury, fibrinogen is cleaved by thrombin to form fibrin which is the most abundant component of blood clots. In addition, various cleavage products of fibrinogen and fibrin regulate cell adhesion and spreading, display vasoconstrictor and chemotactic activities, and are mitogens for several cell types. Mutations in its gene lead to several disorders, including dysfibrinogenemia, hypofibrinogenemia, afibrinogenemia and renal amyloidosis.The protein encoded by this gene is the alpha component of fibrinogen, a blood-borne glycoprotein comprised of three pairs of nonidentical polypeptide chains. Following vascular injury, fibrinogen is cleaved by thrombin to form fibrin which is the most abundant component of blood clots. In addition, various cleavage products of fibrinogen and fibrin regulate cell adhesion and spreading, display vasoconstrictor and chemotactic activities, and are mitogens for several cell types. Mutations in this gene lead to several disorders, including dysfibrinogenemia, hypofibrinogenemia, afibrinogenemia and renal amyloidosis. Alternative splicing results in two isoforms which vary in the carboxy-terminus.
Alias Symbols: Fib2
Protein Interaction Partner: BAT2,CDH5,F13A1,F2,FGA,FGB,FGG,HRG,ITGA2B,ITGB3,NID1,PLAT,SERPINA5,SERPINF2,THBS1,BAT2,CDH5,F13A1,F2,FGA,FGB,FGG,HRG,KHDRBS2,NID1,PLAT,THBS1
Protein Size: 644 -
Poids moléculaire
- 71 kDa
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ID gène
- 2243
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NCBI Accession
- NM_021871, NP_068657
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UniProt
- Q4QQH7
Antigène
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