FK506 Binding Protein 3, 25kDa (FKBP3) Peptide
FKBP3
Reactivité: Humain
Hôte: Synthetic
BP, WB
N° du produit ABIN976872
Aperçu rapide pour FK506 Binding Protein 3, 25kDa (FKBP3) Peptide (ABIN976872)
Antigène
FKBP3
(FK506 Binding Protein 3, 25kDa (FKBP3))
Origine
Humain
Source
Synthetic
Application
Blocking Peptide (BP), Western Blotting (WB)
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Attributs du produit
- This is a synthetic peptide designed for use in combination with anti-FKBP3 antibody (Catalog #: ARP54612_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Purification
- Purified
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Indications d'application
- Each Investigator should determine their own optimal working dilution for specific applications.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Concentration
- 1 mg/mL
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Buffer
- Final peptide concentration is 1 mg/mL in PBS.
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Conseil sur la manipulation
- Avoid repeated freeze-thaw cycles.
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Stock
- -20 °C
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Stockage commentaire
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- FKBP3 (FK506 Binding Protein 3, 25kDa (FKBP3))
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Sujet
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FKBP3 is a member of the immunophilin protein family, which play a role in immunoregulation and basic cellular processes involving protein folding and trafficking. FKBP3 is a cis-trans prolyl isomerase that binds the immunosuppressants FK506 and rapamycin, as well as histone deacetylases, the transcription factor YY1, casein kinase II, and nucleolin. It has a higher affinity for rapamycin than for FK506 and thus may be an important target molecule for immunosuppression by rapamycin.The protein encoded by this gene is a member of the immunophilin protein family, which play a role in immunoregulation and basic cellular processes involving protein folding and trafficking. This encoded protein is a cis-trans prolyl isomerase that binds the immunosuppressants FK506 and rapamycin. It has a higher affinity for rapamycin than for FK506 and thus may be an important target molecule for immunosuppression by rapamycin.
Alias Symbols: FKBP-25, PPIase, FKBP-3, FKBP25
Protein Interaction Partner: CSNK2A1,CSNK2A2,CSNK2B,HDAC1,HDAC2,YY1,HDAC1,HDAC2,MDM2,MTA2,TP53,YY1
Protein Size: 224 -
Poids moléculaire
- 25 kDa
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ID gène
- 2287
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NCBI Accession
- NM_002013, NP_002004
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UniProt
- Q00688
Antigène
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