Fibroblast Growth Factor Receptor Substrate 3 (FRS3) (Middle Region) Peptide
FRS3
Reactivité: Humain
Hôte: Synthetic
BP, WB
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- Antigène Tous les produits FRS3
- FRS3 (Fibroblast Growth Factor Receptor Substrate 3 (FRS3))
- Protein Region
- Middle Region
- Origine
- Humain
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB)
- Attributs du produit
- This is a synthetic peptide designed for use in combination with anti-FRS3 antibody (Catalog #: ARP52228_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- Purification
- Purified
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- Indications d'application
- Each Investigator should determine their own optimal working dilution for specific applications.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Concentration
- 1 mg/mL
- Buffer
- Final peptide concentration is 1 mg/mL in PBS.
- Conseil sur la manipulation
- Avoid repeated freeze-thaw cycles.
- Stock
- -20 °C
- Stockage commentaire
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Antigène
- FRS3 (Fibroblast Growth Factor Receptor Substrate 3 (FRS3))
- Synonymes
- MGC82242 Peptide, snt2 Peptide, frs2b Peptide, snt-2 Peptide, frs2beta Peptide, FRS2-beta Peptide, FRS2B Peptide, FRS2beta Peptide, SNT-2 Peptide, SNT2 Peptide, 4930417B13Rik Peptide, AI449674 Peptide, Frs2beta Peptide, Snt2 Peptide, fibroblast growth factor receptor substrate 3 S homeolog Peptide, fibroblast growth factor receptor substrate 3 Peptide, frs3.S Peptide, FRS3 Peptide, frs3 Peptide, Frs3 Peptide
- Sujet
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FRS3 is an adapter protein that links FGR and NGF receptors to downstream signaling pathways. FRS3 is involved in the activation of MAP kinases. FRS3 down-regulates ERK2 signaling by interfering with the phosphorylation and nuclear translocation of ERK2.The protein encoded by this gene is a substrate for the fibroblast growth factor receptor. It is found in peripheral plasma membrane and functions in linking FGF receptor stimulation to activators of Ras. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: FRS2B, FRS2beta, MGC17167, SNT-2, SNT2
Protein Interaction Partner: FGFR1,NTRK1,PRKCI,BMPR2,FGFR1,GRB2,KARS,MAPK1,NTRK1,NTRK2,PRKCI,PTPN11,RND1,BMPR2,FGFR1
Protein Size: 492 - Poids moléculaire
- 54 kDa
- ID gène
- 10817
- NCBI Accession
- NM_006653, NP_006644
- UniProt
- O43559
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