gamma-aminobutyric Acid (GABA) A Receptor, beta 3 (GABRB3) (Middle Region) Peptide
GABRB3
Reactivité: Humain
Hôte: Synthetic
BP, WB, IHC
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- Antigène Tous les produits GABRB3
- GABRB3 (gamma-aminobutyric Acid (GABA) A Receptor, beta 3 (GABRB3))
- Protein Region
- Middle Region
- Origine
- Humain
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB), Immunohistochemistry (IHC)
- Attributs du produit
- This is a synthetic peptide designed for use in combination with anti-GABRB3 antibody (Catalog #: ARP35339_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- Purification
- Purified
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- Indications d'application
- Each Investigator should determine their own optimal working dilution for specific applications.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Concentration
- 1 mg/mL
- Buffer
- Final peptide concentration is 1 mg/mL in PBS.
- Conseil sur la manipulation
- Avoid repeated freeze-thaw cycles.
- Stock
- -20 °C
- Stockage commentaire
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Antigène
- GABRB3 (gamma-aminobutyric Acid (GABA) A Receptor, beta 3 (GABRB3))
- Synonymes
- GABRB3 Peptide, eca5 Peptide, LOC100230475 Peptide, ECA5 Peptide, A230092K12Rik Peptide, AW049585 Peptide, Cp1 Peptide, Gabrb-3 Peptide, beta3 Peptide, gamma-aminobutyric acid type A receptor beta3 subunit Peptide, gamma-aminobutyric acid (GABA) A receptor, beta 3 Peptide, gamma-aminobutyric acid type A receptor beta 3 subunit Peptide, gamma-aminobutyric acid (GABA) A receptor, subunit beta 3 Peptide, GABRB3 Peptide, gabrb3 Peptide, Gabrb3 Peptide
- Sujet
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GABRB3 is a member of the ligand-gated ionic channel family. GABRB3 is one of at least 13 distinct subunits of a multisubunit chloride channel that serves as the receptor for gamma-aminobutyric acid, the major inhibitory transmitter of the nervous system. Mutations in this gene may be associated with the pathogenesis of Angelman syndrome, Prader-Willi syndrome, and autism.This gene encodes a member of the ligand-gated ionic channel family. The encoded protein is one of at least 13 distinct subunits of a multisubunit chloride channel that serves as the receptor for gamma-aminobutyric acid, the major inhibitory transmitter of the nervous system. This gene is located on the long arm of chromosome 15 in a cluster with two genes encoding related subunits of the family. Mutations in this gene may be associated with the pathogenesis of Angelman syndrome, Prader-Willi syndrome, and autism. Alternatively spliced transcript variants encoding isoforms with distinct signal peptides have been described.
Alias Symbols: MGC9051, ECA5
Protein Interaction Partner: AKAP5,ARFGEF2,GNB2L1,PPP2CA,AKAP5,PRKACA,PRKCA,UBC
Protein Size: 473 - Poids moléculaire
- 52 kDa
- ID gène
- 2562
- NCBI Accession
- NM_021912, NP_068712
- UniProt
- P28472
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