Glucosidase, Beta, Acid (GBA) (C-Term) Peptide
GBA
Reactivité: Humain
Hôte: Synthetic
BP, WB
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- Antigène Tous les produits GBA
- GBA (Glucosidase, Beta, Acid (GBA))
- Protein Region
- C-Term
- Origine
- Humain
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB)
- Séquence
- EGSQRVGLVA SQKNDLDAVA LMHPDGSAVV VVLNRSSKDV PLTIKDPAVG
- Attributs du produit
- This is a synthetic peptide designed for use in combination with anti-GBA Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- Purification
- Purified
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- Indications d'application
- Each Investigator should determine their own optimal working dilution for specific applications.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Concentration
- 1 mg/mL
- Buffer
- Final peptide concentration is 1 mg/mL in PBS.
- Conseil sur la manipulation
- Avoid repeated freeze-thaw cycles.
- Stock
- -20 °C
- Stockage commentaire
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Antigène
- GBA (Glucosidase, Beta, Acid (GBA))
- Synonymes
- GBA1 Peptide, GCB Peptide, GLUC Peptide, BETA-GLUCOSIDASE Peptide, T12J13.8 Peptide, T12J13_8 Peptide, beta glucosidase 25 Peptide, PSPTO3318 Peptide, PSPTO4290 Peptide, GC Peptide, GCase Peptide, betaGC Peptide, glucosylceramidase beta Peptide, beta glucosidase 25 Peptide, beta-glucosidase Peptide, Beta-glucosidase Peptide, glucosidase, beta, acid Peptide, glucosylceramidase Peptide, bglX-2 Peptide, GBA Peptide, BGLU25 Peptide, PSPTO_3318 Peptide, bglX Peptide, bglA4 Peptide, Gba Peptide, LOC100399524 Peptide, bglA.2 Peptide, bglX-2 Peptide
- Sujet
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This gene encodes a lysosomal membrane protein that cleaves the beta-glucosidic linkage of glycosylceramide, an intermediate in glycolipid metabolism. Mutations in this gene cause Gaucher disease, a lysosomal storage disease characterized by an accumulation of glucocerebrosides. A related pseudogene is approximately 12 kb downstream of this gene on chromosome 1. Alternative splicing results in multiple transcript variants.
Alias Symbols: GBA1, GCB, GLUC
Protein Size: 536 - Poids moléculaire
- 59 kDa
- ID gène
- 2629
- NCBI Accession
- NM_000157, NP_000148
- UniProt
- P04062
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