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Gastric Inhibitory Polypeptide Receptor (GIPR) (N-Term) Peptide

GIPR Reactivité: Humain Hôte: Synthetic BP, WB
N° du produit ABIN977412

Aperçu rapide pour Gastric Inhibitory Polypeptide Receptor (GIPR) (N-Term) Peptide (ABIN977412)

Antigène

GIPR (Gastric Inhibitory Polypeptide Receptor (GIPR))

Origine

Humain

Source

  • 3
Synthetic

Application

Blocking Peptide (BP), Western Blotting (WB)
  • Protein Region

    N-Term

    Séquence

    GFVLRQCGSD GQWGLWRDHT QCENPEKNEA FLDQRLILER LQVMYTVGYS

    Attributs du produit

    This is a synthetic peptide designed for use in combination with anti-GIPR Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.

    Purification

    Purified
  • Indications d'application

    Each Investigator should determine their own optimal working dilution for specific applications.

    Restrictions

    For Research Use only
  • Format

    Lyophilized

    Reconstitution

    Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.

    Concentration

    1 mg/mL

    Buffer

    Final peptide concentration is 1 mg/mL in PBS.

    Conseil sur la manipulation

    Avoid repeated freeze-thaw cycles.

    Stock

    -20 °C

    Stockage commentaire

    For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
  • Antigène

    GIPR (Gastric Inhibitory Polypeptide Receptor (GIPR))

    Sujet

    This gene encodes a G-protein coupled receptor for gastric inhibitory polypeptide (GIP), which was originally identified as an activity in gut extracts that inhibited gastric acid secretion and gastrin release, but subsequently was demonstrated to stimulate insulin release in the presence of elevated glucose. Mice lacking this gene exhibit higher blood glucose levels with impaired initial insulin response after oral glucose load. Defect in this gene thus may contribute to the pathogenesis of diabetes.

    Alias Symbols: MGC126722, PGQTL2

    Protein Interaction Partner: GIP,UBC

    Protein Size: 466

    Poids moléculaire

    53 kDa

    ID gène

    2696

    NCBI Accession

    NM_000164, NP_000155

    UniProt

    P48546
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