Glutamate Receptor, Metabotropic 7 (GRM7) (C-Term) Peptide
GRM7
Reactivité: Humain
Hôte: Synthetic
BP, WB
N° du produit ABIN977702
150,78 €
Plus frais de livraison 40,00 € et TVA
100 μg
Destination:
France
Envoi sous 15 à 22 jours ouvrables
Aperçu rapide pour Glutamate Receptor, Metabotropic 7 (GRM7) (C-Term) Peptide (ABIN977702)
Antigène
GRM7
(Glutamate Receptor, Metabotropic 7 (GRM7))
Origine
Humain
Source
Synthetic
Application
Blocking Peptide (BP), Western Blotting (WB)
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Protein Region
- C-Term
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Séquence
- HPELNVQKRK RSFKAVVTAA TMSSRLSHKP SDRPNGEAKT ELCENVDPNS
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Attributs du produit
- This is a synthetic peptide designed for use in combination with anti-GRM7 Antibody(ARP59604_P050),. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Purification
- Purified
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Glutamate Receptor, Metabotropic 7 (GRM7) peptide
GRM7 Reactivité: Humain, Souris, Rat Hôte: Synthetic BP, Imm
Glutamate Receptor, Metabotropic 7 (GRM7) peptideGRM7 Hôte: Synthetic BP, WB, IHC
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Indications d'application
- Each Investigator should determine their own optimal working dilution for specific applications.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Concentration
- 1 mg/mL
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Buffer
- Final peptide concentration is 1 mg/mL in PBS.
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Conseil sur la manipulation
- Avoid repeated freeze-thaw cycles.
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Stock
- -20 °C
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Stockage commentaire
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- GRM7 (Glutamate Receptor, Metabotropic 7 (GRM7))
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Sujet
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L-glutamate is the major excitatory neurotransmitter in the central nervous system, and it activates both ionotropic and metabotropic glutamate receptors. Glutamatergic neurotransmission is involved in most aspects of normal brain function and can be perturbed in many neuropathologic conditions. The metabotropic glutamate receptors are a family of G protein-coupled receptors that have been divided into three groups on the basis of sequence homology, putative signal transduction mechanisms, and pharmacologic properties. Group I includes GRM1 and GRM5, and these receptors have been shown to activate phospholipase C. Group II includes GRM2 and GRM3, while Group III includes GRM4, GRM6, GRM7 and GRM8. Group II and III receptors are linked to the inhibition of the cyclic AMP cascade but differ in their agonist selectivities. Multiple transcript variants encoding different isoforms have been found for this gene.
Alias Symbols: FLJ40498, GLUR7, GPRC1G, MGLU7, MGLUR7
Protein Interaction Partner: GRIP1,PICK1,SDCBP,CALM1,CALM3,CALM3,FLNA,GNAQ,GRIPAP1,PICK1,TUBA1A,TUBA1B,TUBA3C,TUBA4A,TUBA8,GNAQ,PICK1,PRKCA
Protein Size: 915 -
Poids moléculaire
- 99 kDa
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ID gène
- 2917
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NCBI Accession
- NM_000844, NP_000835
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UniProt
- Q14831
Antigène
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