H2A Histone Family, Member Z (H2AFZ) (N-Term) Peptide
Aperçu rapide pour H2A Histone Family, Member Z (H2AFZ) (N-Term) Peptide (ABIN977829)
Antigène
Origine
Source
Application
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Protein Region
- N-Term
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Séquence
- AGGKAGKDSG KAKTKAVSRS QRAGLQFPVG RIHRHLKSRT TSHGRVGATA
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Attributs du produit
- This is a synthetic peptide designed for use in combination with anti-H2AFZ Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Purification
- Purified
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Indications d'application
- Each Investigator should determine their own optimal working dilution for specific applications.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Concentration
- 1 mg/mL
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Buffer
- Final peptide concentration is 1 mg/mL in PBS.
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Conseil sur la manipulation
- Avoid repeated freeze-thaw cycles.
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Stock
- -20 °C
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Stockage commentaire
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- H2AFZ (H2A Histone Family, Member Z (H2AFZ))
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Sujet
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Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Nucleosomes consist of approximately 146 bp of DNA wrapped around a histone octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures. This gene encodes a replication-independent member of the histone H2A family that is distinct from other members of the family. Studies in mice have shown that this particular histone is required for embryonic development and indicate that lack of functional histone H2A leads to embryonic lethality.
Alias Symbols: H2A.z, H2A/z, H2AZ, MGC117173
Protein Interaction Partner: H2AFZ,INCENP,MAGEC1,CHD1L,INCENP,tat
Protein Size: 128 -
Poids moléculaire
- 14 kDa
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ID gène
- 3015
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NCBI Accession
- NM_002106, NP_002097
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UniProt
- P0C0S5
Antigène
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