This is a synthetic peptide designed for use in combination with anti-HIST1H3A Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
Each Investigator should determine their own optimal working dilution for specific applications.
Restrictions
For Research Use only
Format
Lyophilized
Reconstitution
Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
Concentration
1 mg/mL
Buffer
Final peptide concentration is 1 mg/mL in PBS.
Conseil sur la manipulation
Avoid repeated freeze-thaw cycles.
Stock
-20 °C
Stockage commentaire
For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
Antigène
HIST1H3A
(Histone Cluster 1, H3a (HIST1H3A))
Synonymes
H3/A Peptide, H3FA Peptide, histone cluster 1 H3 family member a Peptide, histone cluster 1, H3a Peptide, HIST1H3A Peptide, Hist1h3a Peptide
Sujet
Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. This structure consists of approximately 146 bp of DNA wrapped around a nucleosome, an octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures. This gene is intronless and encodes a member of the histone H3 family. Transcripts from this gene lack polyA tails, instead, they contain a palindromic termination element. This gene is found in the large histone gene cluster on chromosome 6p22-p21.3.
Protein Interaction Partner: AURKB,CBX1,RAD51L1,SETDB1,SUV39H1,UHRF1,ALL1,ANP32A,ASF1A,ASF1B,ASH1L,ASH2L,AT3G49660,ATRX,AURKB,BAZ1B,BPTF,CALCOCO1,CARM1,CBX1,CBX3,CBX5,CBX7,CDYL,CHAF1A,CHAF1B,CHD1,CHD3,CREBBP,CTCFL,CUL4A,DDB1,DEK,DNMT3A,DYRK1A,EED,EGLN1,EHMT1,EHMT2,EID1,EP300,ERCC6,EZ