HLA Class I alpha F (HLAF) (N-Term) Peptide
HLAF
Reactivité: Humain
Hôte: Synthetic
BP, WB
N° du produit ABIN978029
Aperçu rapide pour HLA Class I alpha F (HLAF) (N-Term) Peptide (ABIN978029)
Antigène
HLA-F (HLAF)
(HLA Class I alpha F (HLAF))
Origine
Humain
Source
Synthetic
Application
Blocking Peptide (BP), Western Blotting (WB)
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Protein Region
- N-Term
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Séquence
- PWVEQEGPQY WEWTTGYAKA NAQTDRVALR NLLRRYNQSE AGSHTLQGMN
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Attributs du produit
- This is a synthetic peptide designed for use in combination with anti-HLA-F Antibody(ARP49410_P050),. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Purification
- Purified
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Indications d'application
- Each Investigator should determine their own optimal working dilution for specific applications.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Concentration
- 1 mg/mL
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Buffer
- Final peptide concentration is 1 mg/mL in PBS.
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Conseil sur la manipulation
- Avoid repeated freeze-thaw cycles.
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Stock
- -20 °C
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Stockage commentaire
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- HLA-F (HLAF) (HLA Class I alpha F (HLAF))
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Sujet
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HLA-F belongs to the HLA class I heavy chain paralogues. It is a non-classical heavy chain that forms a heterodimer with a beta-2 microglobulin light chain, with the heavy chain anchored in the membrane. Unlike most other HLA heavy chains, this molecule is localized in the endoplasmic reticulum and Golgi apparatus, with a small amount present at the cell surface in some cell types. It contains a divergent peptide-binding groove, and is thought to bind a restricted subset of peptides for immune presentation.
Alias Symbols: CDA12, HLA-5.4, HLA-CDA12, HLAF
Protein Interaction Partner: B2M,HLA-F,LILRB1,LILRB2,TAP1,LILRB1,LILRB2
Protein Size: 442 -
Poids moléculaire
- 48 kDa
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ID gène
- 3134
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NCBI Accession
- NM_001098479, NP_001091949
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UniProt
- Q5JQI8
Antigène
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