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High Mobility Group AT-Hook 1 (HMGA1) (N-Term) Peptide

HMGA1 Reactivité: Humain Hôte: Synthetic BP, WB
N° du produit ABIN978048
  • Antigène Tous les produits HMGA1
    HMGA1 (High Mobility Group AT-Hook 1 (HMGA1))
    Protein Region
    N-Term
    Origine
    Humain
    Source
    • 7
    Synthetic
    Application
    Blocking Peptide (BP), Western Blotting (WB)
    Séquence
    MSESSSKSSQ PLASKQEKDG TEKRGRGRPR KQPPKEPSEV PTPKRPRGRP
    Attributs du produit
    This is a synthetic peptide designed for use in combination with anti-HMGA1 Antibody(ARP38111_P050),. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
    Purification
    Purified
  • Indications d'application
    Each Investigator should determine their own optimal working dilution for specific applications.
    Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
    Concentration
    1 mg/mL
    Buffer
    Final peptide concentration is 1 mg/mL in PBS.
    Conseil sur la manipulation
    Avoid repeated freeze-thaw cycles.
    Stock
    -20 °C
    Stockage commentaire
    For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
  • Antigène
    HMGA1 (High Mobility Group AT-Hook 1 (HMGA1))
    Synonymes
    HMG-R Peptide, HMGA1A Peptide, HMGIY Peptide, Hmgi Peptide, Hmgiy Peptide, hmga1 Peptide, hmgiy Peptide, wu:fb12b06 Peptide, wu:fb18f11 Peptide, wu:fc19f01 Peptide, wu:fi38b05 Peptide, zgc:85677 Peptide, AL023995 Peptide, Hmga1a Peptide, Hmga1b Peptide, Hmgy Peptide, HMG-I(Y) Peptide, HMG-Y Peptide, HMGA1 Peptide, zgc:153948 Peptide, high mobility group AT-hook 1 Peptide, high mobility group protein HMG-I/HMG-Y Peptide, high mobility group AT-hook 1a Peptide, high mobility group AT-hook 1b Peptide, HMGA1 Peptide, Hmga1 Peptide, TSC_c24220 Peptide, hmga1a Peptide, LOC705105 Peptide, hmga1b Peptide
    Sujet
    This gene encodes a non-histone protein involved in many cellular processes, including regulation of inducible gene transcription, integration of retroviruses into chromosomes, and the metastatic progression of cancer cells. The encoded protein preferentially binds to the minor groove of A+T-rich regions in double-stranded DNA. It has little secondary structure in solution but assumes distinct conformations when bound to substrates such as DNA or other proteins. The encoded protein is frequently acetylated and is found in the nucleus. At least seven transcript variants encoding two different isoforms have been found for this gene.

    Alias Symbols: HMG-R, HMGA1A, HMGIY, MGC12816, MGC4242, MGC4854

    Protein Interaction Partner: ATF2,CDK1,CEBPB,CREBBP,CSNK2A1,CSNK2A2,ELF1,EWSR1,HIPK2,IRF1,JUN,NFYA,POU3F1,PPARG,PRMT6,RARG,RNF4,RXRA,SP1,SRF,SUFU,ATF2,BANF1,CEBPB,CHD1,ELF1,EWSR1,INSR,IRF1,JUN,NFYA,NPM1,PARP1,POU3F1,PPARG,PRMT6,SP1

    Protein Size: 96
    Poids moléculaire
    11 kDa
    ID gène
    3159
    NCBI Accession
    NM_002131, NP_002122
    UniProt
    Q5T6U8
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